Mobyle: a new full web bioinformatics framework
Motivation: For the biologist, running bioinformatics analyses involves a time-consuming
management of data and tools. Users need support to organize their work, retrieve parameters …
management of data and tools. Users need support to organize their work, retrieve parameters …
[HTML][HTML] Gene flow contributes to diversification of the major fungal pathogen Candida albicans
J Ropars, C Maufrais, D Diogo… - Nature …, 2018 - nature.com
Elucidating population structure and levels of genetic diversity and recombination is necessary
to understand the evolution and adaptation of species. Candida albicans is the second …
to understand the evolution and adaptation of species. Candida albicans is the second …
[HTML][HTML] A preliminary study of viral metagenomics of French bat species in contact with humans: identification of new mammalian viruses
…, JM Thiberge, M Vandenbogaert, C Maufrais… - PloS one, 2014 - journals.plos.org
The prediction of viral zoonosis epidemics has become a major public health issue. A
profound understanding of the viral population in key animal species acting as reservoirs …
profound understanding of the viral population in key animal species acting as reservoirs …
Candidalysins are a new family of cytolytic fungal peptide toxins
Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen.
Candidalysin is secreted by Candida albicans and is critical for driving infection and host …
Candidalysin is secreted by Candida albicans and is critical for driving infection and host …
[HTML][HTML] Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation
…, T Douche, J Guglielmini, A Criscuolo, C Maufrais… - Scientific reports, 2017 - nature.com
The RpoS/σ S sigma subunit of RNA polymerase is the master regulator of the general stress
response in many Gram-negative bacteria. Extensive studies have been conducted on σ S -…
response in many Gram-negative bacteria. Extensive studies have been conducted on σ S -…
Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans
Aneuploidy is a frequent occurrence in fungal species where it can alter gene expression
and promote adaptation to a variety of environmental cues. Multiple forms of aneuploidy have …
and promote adaptation to a variety of environmental cues. Multiple forms of aneuploidy have …
Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom
EWJ Wallace, C Maufrais, J Sales-Lee… - Nucleic Acids …, 2020 - academic.oup.com
Eukaryotic protein synthesis generally initiates at a start codon defined by an AUG and its
surrounding Kozak sequence context, but the quantitative importance of this context in different …
surrounding Kozak sequence context, but the quantitative importance of this context in different …
[HTML][HTML] Within-Host Genomic Diversity of Candida albicans in Healthy Carriers
E Sitterlé, C Maufrais, N Sertour, M Palayret… - Scientific reports, 2019 - nature.com
Genomic variations in Candida albicans, a major fungal pathogen of humans, have been
observed upon exposure of this yeast to different stresses and experimental infections, …
observed upon exposure of this yeast to different stresses and experimental infections, …
Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans
J Rizzo, A Trottier, F Moyrand, JY Coppée, C Maufrais… - MBio, 2023 - Am Soc Microbiol
Resistance to fluconazole (FLC), the most widely used antifungal drug, is typically achieved
by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a …
by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a …
Androctonin, a Novel Antimicrobial Peptide from Scorpion Androctonus Australis: Solution Structure and Molecular Dynamics Simulations in the Presence of a Lipid …
N Mandard, D Sy, C Maufrais… - Journal of …, 1999 - Taylor & Francis
Androctonin is a highly cationic antimicrobial peptide from scorpion exhibiting a broad spectrum
of activities against bacteria and fungi. It contains 25 amino acids including four cysteine …
of activities against bacteria and fungi. It contains 25 amino acids including four cysteine …