Mobyle: a new full web bioinformatics framework

B Néron, H Ménager, C Maufrais, N Joly… - …, 2009 - academic.oup.com
Motivation: For the biologist, running bioinformatics analyses involves a time-consuming
management of data and tools. Users need support to organize their work, retrieve parameters …

[HTML][HTML] Gene flow contributes to diversification of the major fungal pathogen Candida albicans

J Ropars, C Maufrais, D Diogo… - Nature …, 2018 - nature.com
Elucidating population structure and levels of genetic diversity and recombination is necessary
to understand the evolution and adaptation of species. Candida albicans is the second …

[HTML][HTML] A preliminary study of viral metagenomics of French bat species in contact with humans: identification of new mammalian viruses

…, JM Thiberge, M Vandenbogaert, C Maufrais… - PloS one, 2014 - journals.plos.org
The prediction of viral zoonosis epidemics has become a major public health issue. A
profound understanding of the viral population in key animal species acting as reservoirs …

Candidalysins are a new family of cytolytic fungal peptide toxins

…, N Kichik, S Lee, E Priest, S Mogavero, C Maufrais… - MBio, 2022 - Am Soc Microbiol
Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen.
Candidalysin is secreted by Candida albicans and is critical for driving infection and host …

[HTML][HTML] Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation

…, T Douche, J Guglielmini, A Criscuolo, C Maufrais… - Scientific reports, 2017 - nature.com
The RpoS/σ S sigma subunit of RNA polymerase is the master regulator of the general stress
response in many Gram-negative bacteria. Extensive studies have been conducted on σ S -…

Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans

P Kakade, S Sircaik, C Maufrais… - Proceedings of the …, 2023 - National Acad Sciences
Aneuploidy is a frequent occurrence in fungal species where it can alter gene expression
and promote adaptation to a variety of environmental cues. Multiple forms of aneuploidy have …

Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom

EWJ Wallace, C Maufrais, J Sales-Lee… - Nucleic Acids …, 2020 - academic.oup.com
Eukaryotic protein synthesis generally initiates at a start codon defined by an AUG and its
surrounding Kozak sequence context, but the quantitative importance of this context in different …

[HTML][HTML] Within-Host Genomic Diversity of Candida albicans in Healthy Carriers

E Sitterlé, C Maufrais, N Sertour, M Palayret… - Scientific reports, 2019 - nature.com
Genomic variations in Candida albicans, a major fungal pathogen of humans, have been
observed upon exposure of this yeast to different stresses and experimental infections, …

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans

J Rizzo, A Trottier, F Moyrand, JY Coppée, C Maufrais… - MBio, 2023 - Am Soc Microbiol
Resistance to fluconazole (FLC), the most widely used antifungal drug, is typically achieved
by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a …

Androctonin, a Novel Antimicrobial Peptide from Scorpion Androctonus Australis: Solution Structure and Molecular Dynamics Simulations in the Presence of a Lipid …

N Mandard, D Sy, C Maufrais… - Journal of …, 1999 - Taylor & Francis
Androctonin is a highly cationic antimicrobial peptide from scorpion exhibiting a broad spectrum
of activities against bacteria and fungi. It contains 25 amino acids including four cysteine …