EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus–infected B cells

…, LE Wange, X Zhang, C Kuklik-Roos… - Proceedings of the …, 2022 - National Acad Sciences
Epstein-Barr virus (EBV) is a human tumor virus which preferentially infects resting human B
cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …

[HTML][HTML] Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis

…, L Hültner, M Schneider, C Ladinig, C Kuklik-Roos… - …, 2020 - ncbi.nlm.nih.gov
Glutathione peroxidase 4 (GPX4) is unique as it is the only enzyme that can prevent detrimental
lipid peroxidation in vivo by reducing lipid peroxides to the respective alcohols thereby …

[HTML][HTML] EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells

…, S Rieger, S Thumann, S Beer, C Kuklik-Roos… - PLoS …, 2017 - journals.plos.org
Epstein-Barr virus (EBV) infection converts resting human B cells into permanently proliferating
lymphoblastoid cell lines (LCLs). The Epstein-Barr virus nuclear antigen 2 (EBNA2) plays …

Enhancement of Epstein-Barr virus membrane protein (LMP) expression by serum, TPA, or n-butyrate in latently infected Raji cells

H Boos, R Berger, C Kuklik-Roos, T Iftner… - Virology, 1987 - Elsevier
The BamHI Nhet region of the EBV DNA is known to code for two proteins. One is a
membrane protein (LMP) with an apparent molecular weight of 60,000 on SDS-PAGE which is …

PLK1‐dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV‐infected mice

…, P Giansanti, A Murer, S Thumann, C KuklikRoos… - EMBO …, 2021 - embopress.org
While Epstein–Barr virus (EBV) establishes a life‐long latent infection in apparently healthy
human immunocompetent hosts, immunodeficient individuals are at particular risk to develop …

The EBNA2-EBF1 complex promotes oncogenic MYC expression levels and metabolic processes required for cell cycle progression of Epstein-Barr virus-infected B …

S Beer, LE Wange, X Zhang, C Kuklik-Roos, W Enard… - bioRxiv, 2021 - biorxiv.org
Epstein-Barr virus (EBV) is a human tumor virus, which preferentially infects resting human
B cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …

Inhibition of PLK1-dependent EBNA2 phosphorylation promotes lymphomagenesis in EBV-infected mice

…, P Giansanti, A Murer, S Thumann, C Kuklik-Roos… - bioRxiv, 2021 - biorxiv.org
While Epstein-Barr virus (EBV) establishes a life-long latent infection in apparently healthy
human immunocompetent hosts, immunodeficient individuals are at particular risk to develop …

Epstein-Barr Virus Protein (LMP) Expression is Enhanced by Serum, TPA or Butyrate

H Boos, R Berger, C Kuklik-Roos… - Epstein-Barr Virus and …, 1987 - Springer
So far, four viral genes are found to be expressed in latently EBV-infected cells (1, 2, 3, 4, 5,
6). These genes are coding for at least three EBNA associated nuclear proteins and one …

Identification of the coding region for a second Epstein‐Barr virus nuclear antigen (EBNA 2) by transfection of cloned DNA fragments.

…, M Sauter, K Takaki, JM Béchet, C KuklikRoos… - The EMBO …, 1985 - embopress.org
Cell lines were established by co‐transfection of cloned M‐ABA Epstein‐Barr virus (EBV)
DNA fragments with plasmids conferring resistance to dominant selective markers. A baby …

Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis

T Schroeder, ST Fraser, M Ogawa… - Proceedings of the …, 2003 - National Acad Sciences
… Hitoshi Niwa for providing the pCAG-IP construct and Cornelia Kuklik-Roos, Hanna Eilken,
and Heike Knetsch for expert technical assistance. This work was supported by grants from …