User profiles for Craig B Wilen
 | Craig B. Wilen, MD, PhDAssociate Professor, Yale University Verified email at yale.edu Cited by 13599 |
Neuroinvasion of SARS-CoV-2 in human and mouse brain
… CB Wilen reported personal fees from ZymoResearch outside the submitted work; in addition,
CB Wilen had a patent for compounds and compositions for treating, ameliorating, and/or …
CB Wilen had a patent for compounds and compositions for treating, ameliorating, and/or …
[HTML][HTML] Inflammasome activation in infected macrophages drives COVID-19 pathology
Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine
production, viral RNA and a sustained interferon (IFN) response, all of which are recapitulated …
production, viral RNA and a sustained interferon (IFN) response, all of which are recapitulated …
HIV: cell binding and entry
The first step of the human immunodeficiency virus (HIV) replication cycle—binding and entry
into the host cell—plays a major role in determining viral tropism and the ability of HIV to …
into the host cell—plays a major role in determining viral tropism and the ability of HIV to …
[PDF][PDF] Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection may reveal novel therapeutic targets and inform our understanding of …
infection may reveal novel therapeutic targets and inform our understanding of …
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling
Severe acute respiratory syndrome–coronavirus 2 (SARS-Cov-2) has caused over 13,000,000
cases of coronavirus disease (COVID-19) with a significant fatality rate. Laboratory mice …
cases of coronavirus disease (COVID-19) with a significant fatality rate. Laboratory mice …
Phenotypic properties of transmitted founder HIV-1
…, AP West Jr, PJ Bjorkman, CB Wilen… - Proceedings of the …, 2013 - National Acad Sciences
Defining the virus–host interactions responsible for HIV-1 transmission, including the phenotypic
requirements of viruses capable of establishing de novo infections, could be important …
requirements of viruses capable of establishing de novo infections, could be important …
[PDF][PDF] Altered virome and bacterial microbiome in human immunodeficiency virus-associated acquired immunodeficiency syndrome
Human immunodeficiency virus (HIV) infection is associated with increased intestinal
translocation of microbial products and enteropathy as well as alterations in gut bacterial …
translocation of microbial products and enteropathy as well as alterations in gut bacterial …
Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein
The ongoing COVID-19 pandemic has caused an unprecedented global health crisis. Severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-…
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-…
[HTML][HTML] Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of symptoms
in infected individuals, from mild respiratory illness to acute respiratory distress syndrome. …
in infected individuals, from mild respiratory illness to acute respiratory distress syndrome. …
[PDF][PDF] Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms
Severe-acute-respiratory-syndrome-related coronavirus 2 (SARS-CoV-2) is the positive-sense
RNA virus that causes coronavirus disease 2019 (COVID-19). The genome of SARS-CoV-…
RNA virus that causes coronavirus disease 2019 (COVID-19). The genome of SARS-CoV-…