The use of lipid-formulated RNA vaccines for cancer or COVID-19 is associated with dose-limiting
systemic inflammatory responses in humans that were not predicted from preclinical …

Spontaneous interaction of purified apolipoproteins and phospholipids results in formation
of lipoprotein particles with nanometer-sized dimensions; we refer to these assemblies as …

Here we demonstrate rapid production of solubilized and functional membrane protein by
simultaneous cell-free expression of an apolipoprotein and a membrane protein in the …

We review structure and dynamic measurements of biomembranes by atomic force microscopy
(AFM). We focus mainly on studies involving supported lipid bilayers (SLBs), particularly …

A fundamental attribute of cell membranes is transmembrane asymmetry, specifically the
formation of ordered phase domains in one leaflet that are compositionally different from the …

Profound global loss of DNA methylation is a hallmark of many cancers. One potential
consequence of this is the reactivation of transposable elements (TEs) which could stimulate the …

We report a cell-free approach for expressing and inserting integral membrane proteins into
water-soluble particles composed of discoidal apolipoprotein−lipid bilayers. Proteins are …

An industrial process for the selective activation of methane under mild conditions would be
highly valuable for controlling emissions to the environment and for utilizing vast new …

Subunit antigen-based vaccines can provide a number of important benefits over traditional
vaccine candidates, such as overall safety. However, because of the inherently low …

The broad application of precision cancer immunotherapies is limited by the number of
validated neoepitopes that are common among patients or tumor types. To expand the known …