Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis

M Kalyna, CG Simpson, NH Syed… - Nucleic acids …, 2012 - academic.oup.com
Alternative splicing (AS) coupled to nonsense-mediated decay (NMD) is a post-transcriptional
mechanism for regulating gene expression. We have used a high-resolution AS RT–PCR …

[HTML][HTML] Long noncoding RNA modulates alternative splicing regulators in Arabidopsis

F Bardou, F Ariel, CG Simpson, N Romero-Barrios… - Developmental cell, 2014 - cell.com
Alternative splicing (AS) of pre-mRNA represents a major mechanism underlying increased
transcriptome and proteome complexity. Here, we show that the nuclear speckle RNA-…

A methyl transferase links the circadian clock to the regulation of alternative splicing

…, MA Godoy Herz, A Depetris-Chauvin, CG Simpson… - Nature, 2010 - nature.com
Circadian rhythms allow organisms to time biological processes to the most appropriate
phases of the day–night cycle 1 . Post-transcriptional regulation is emerging as an important …

Physiological, biochemical and molecular responses of the potato (Solanum tuberosum L.) plant to moderately elevated temperature

…, SR Verrall, J Fuller, CG Simpson… - Plant, cell & …, 2014 - Wiley Online Library
Although significant work has been undertaken regarding the response of model and crop
plants to heat shock during the acclimatory phase, few studies have examined the steady‐…

An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana

C Streitner, T Köster, CG Simpson, P Shaw… - Nucleic acids …, 2012 - academic.oup.com
Alternative splicing (AS) of pre-mRNAs is an important regulatory mechanism shaping the
transcriptome. In plants, only few RNA-binding proteins are known to affect AS. Here, we show …

Mutation of Arabidopsis SPLICEOSOMAL TIMEKEEPER LOCUS1 Causes Circadian Clock Defects

MA Jones, BA Williams, J McNicol, CG Simpson… - The Plant …, 2012 - academic.oup.com
The circadian clock plays a crucial role in coordinating plant metabolic and physiological
functions with predictable environmental variables, such as dusk and dawn, while also …

The spliceosome assembly factor GEMIN2 attenuates the effects of temperature on alternative splicing and circadian rhythms

…, ML Rugnone, CG Simpson… - Proceedings of the …, 2015 - National Acad Sciences
The mechanisms by which poikilothermic organisms ensure that biological processes are
robust to temperature changes are largely unknown. Temperature compensation, the ability of …

The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana

…, M Bajczyk, J McNicol, CG Simpson… - Nucleic acids …, 2013 - academic.oup.com
How alternative splicing (AS) is regulated in plants has not yet been elucidated. Previously,
we have shown that the nuclear cap-binding protein complex (AtCBC) is involved in AS in …

Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana

KD Raczynska, CG Simpson, A Ciesiolka… - Nucleic Acids …, 2010 - academic.oup.com
The nuclear cap-binding protein complex (CBC) participates in 5′ splice site selection of
introns that are proximal to the mRNA cap. However, it is not known whether CBC has a role in …

The Arabidopsis SR45 splicing factor, a negative regulator of sugar signaling, modulates SNF1-related protein kinase 1 stability

RF Carvalho, D Szakonyi, CG Simpson… - The Plant …, 2016 - academic.oup.com
The ability to sense and respond to sugar signals allows plants to cope with environmental
and metabolic changes by adjusting growth and development accordingly. We previously …