User profiles for Craig T. Jordan
 | Craig T JordanProfessor or Medicine, University of Colorado Verified email at cuanschutz.edu Cited by 29198 |
[PDF][PDF] BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells
…, JL Liesveld, PS Brookes, MW Becker, CT Jordan - Cell stem cell, 2013 - cell.com
Most forms of chemotherapy employ mechanisms involving induction of oxidative stress, a
strategy that can be effective due to the elevated oxidative state commonly observed in cancer …
strategy that can be effective due to the elevated oxidative state commonly observed in cancer …
Functional genomic landscape of acute myeloid leukaemia
The implementation of targeted therapies for acute myeloid leukaemia (AML) has been
challenging because of the complex mutational patterns within and across patients as well as a …
challenging because of the complex mutational patterns within and across patients as well as a …
The increasing complexity of the cancer stem cell paradigm
The investigation and study of cancer stem cells (CSCs) have received enormous attention
over the past 5 to 10 years but remain topics of considerable controversy. Opinions about the …
over the past 5 to 10 years but remain topics of considerable controversy. Opinions about the …
Cancer stem cells
Cancer Stem Cells | NEJM Skip to main content NEJM Group Follow Us Facebook Twitter
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Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge, lead a …
Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells
Human acute myelogenous leukemia (AML) is thought to arise from a rare population of
malignant stem cells. Cells of this nature, herein referred to as leukemic stem cells (LSCs), have …
malignant stem cells. Cells of this nature, herein referred to as leukemic stem cells (LSCs), have …
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
…, X Li, DR Peterson, DS Howard, CT Jordan - Blood, 2005 - ashpublications.org
Recent studies have described malignant stem cells as central to the initiation, growth, and
potential relapse of acute and chronic myelogenous leukemia (AML and CML). Because of …
potential relapse of acute and chronic myelogenous leukemia (AML and CML). Because of …
A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations
To elucidate the molecular biology of the hematopoietic stem cell, we have begun to isolate
genes from murine cell populations enriched in stem cell activity. One such cDNA encodes a …
genes from murine cell populations enriched in stem cell activity. One such cDNA encodes a …
Clonal and systemic analysis of long-term hematopoiesis in the mouse.
CT Jordan, IR Lemischka - Genes & development, 1990 - genesdev.cshlp.org
We have analyzed the temporal in vivo fate of 142 individual stem cell clones in 63
reconstituted mice. Long-term sequential analyses of the four major peripheral blood lineages, …
reconstituted mice. Long-term sequential analyses of the four major peripheral blood lineages, …
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.
We have cloned a receptor tyrosine kinase cDNA, designated fetal liver kinase 1 (Flk-1), from
mouse cell populations enriched for hematopoietic stem and progenitor cells. Sequence …
mouse cell populations enriched for hematopoietic stem and progenitor cells. Sequence …
Preferential induction of apoptosis for primary human leukemic stem cells
…, RM Rossi, SJ Szilvassy, CT Jordan - Proceedings of the …, 2002 - National Acad Sciences
Acute myelogenous leukemia (AML) is typically a disease of stem/progenitor cell origin.
Interestingly, the leukemic stem cell (LSC) shares many characteristics with normal …
Interestingly, the leukemic stem cell (LSC) shares many characteristics with normal …