Antiviral activity of cationic amphiphilic drugs

C Salata, A Calistri, C Parolin… - Expert review of anti …, 2017 - Taylor & Francis
Introduction: Emerging and reemerging viral infections represent a major concern for human
and veterinary public health and there is an urgent need for the development of broad-…

Intracellular trafficking and maturation of herpes simplex virus type 1 gB and virus egress require functional biogenesis of multivesicular bodies

A Calistri, P Sette, C Salata, E Cancellotti… - Journal of …, 2007 - Am Soc Microbiol
The biogenesis of multivesicular bodies (MVBs) is topologically equivalent to virion budding.
Hence, a number of viruses exploit the MVB pathway to build their envelope and exit from …

Involvement of p53 in specific anti‐neuroectodermal tumor activity of aloe‐emodin

T Pecere, F Sarinella, C Salata, B Gatto… - … journal of cancer, 2003 - Wiley Online Library
Previously, we have identified aloe‐emodin (AE) as a new type of anticancer agent, with
activity that is based on apoptotic cell death promoted by a neuroectodermal tumor‐specific …

[HTML][HTML] Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

V Monteil, H Kwon, L John, C Salata, G Jonsson… - Nature …, 2023 - nature.com
Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks
have occurred in the last decades. Although several receptors and co-receptors have …

[HTML][HTML] Ebola virus entry: from molecular characterization to drug discovery

C Salata, A Calistri, G Alvisi, M Celestino, C Parolin… - Viruses, 2019 - mdpi.com
Ebola Virus Disease (EVD) is one of the most lethal transmissible infections, characterized
by a high fatality rate, and caused by a member of the Filoviridae family. The recent large …

Coronaviruses: a paradigm of new emerging zoonotic diseases

C Salata, A Calistri, C Parolin, G Palu - Pathogens and disease, 2019 - academic.oup.com
A novel type of coronavirus (2019-nCoV) infecting humans appeared in Wuhan, China, at the
end of December 2019. Since the identification of the outbreak the infection quickly spread …

Role of multivesicular bodies and their components in the egress of enveloped RNA viruses

A Calistri, C Salata, C Parolin… - Reviews in medical …, 2009 - Wiley Online Library
As an enveloped virus buds, the nascent viral capsid becomes wrapped in a plasma
membrane‐derived lipid envelope, and a membrane fission event is thus necessary to separate the …

Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process

C Salata, A Baritussio, D Munegato… - Pathogens and …, 2015 - academic.oup.com
Ebola virus disease (EVD) is one of the most lethal transmissible infections characterized by
a high fatality rate, and a treatment has not been developed yet. Recently, it has been …

[HTML][HTML] Hypothiocyanite and hypothiocyanite/lactoferrin mixture exhibit virucidal activity in vitro against SARS-CoV-2

…, C Salaris, MV Salvati, G Mastrangelo, C Salata - Pathogens, 2021 - mdpi.com
… LC and CS (Cristiano Salata) conceived the project and wrote the draft. CS (Cristiano
Salata) propagated the SARS-CoV-2, performed experiments with SARS-CoV-2, provided …

[HTML][HTML] Human endogenous retroviruses and cancer prevention: evidence and prospects

L Cegolon, C Salata, E Weiderpass, P Vineis, G Palù… - BMC cancer, 2013 - Springer
Background Cancer is a significant and growing problem worldwide. While this increase
may, in part, be attributed to increasing longevity, improved case notifications and risk-…