TransMEMbrane 16A (TMEM16A) is a Ca 2+ -activated Cl − channel that plays critical roles
in regulating diverse physiologic processes, including vascular tone, sensory signal …

The Ca 2+ activated Cl − channel formed by transmembrane member 16A (TMEM16A) is
broadly expressed and regulates diverse processes. In addition to Ca 2+ , TMEM16A channels …

Transmembrane protein 16A (TMEM16A) is a widely expressed calcium-activated chloride
channel that regulates diverse processes, including inflammation, coronary blood flow, and …

Cancer remains a leading cause of death worldwide due to the lack of safer and more
effective therapies. Cancer vaccines developed from neoantigens are an emerging strategy to …

Circulating tumour cells (CTCs) originating from a primary tumour, lymph nodes and distant
metastases hold great potential for liquid biopsies by providing a molecular fingerprint for …

… 75 μl of conditioned medium was removed from the wells and 50 µl of DMSO (Sigma-Aldrich)
was added to solubilize formazan crystals. Plates were incubated at 37 C for 10 min and …

Advanced-stage solid primary tumors and metastases often express mucin 16 (MUC16),
carrying immature glycans such as the Tn antigen, resulting in specific glycoproteoforms not …

… Conditioned medium was removed and 50 μL of DMSO (Sigma-Aldrich) was added to
solubilize formazan crystals. Plates were incubated at 37 C for 10 min and absorbances were …

Globally, gastric cancer is the 4 th most frequently diagnosed cancer and the 2 nd leading
cause of death from cancer, with an estimated 990000 new cases and 738000 deaths …

Bladder cancer constitutes one of the deadliest genitourinary diseases, especially when
diagnosed at late stages. These tumours harbour microenvironmental niches characterized by …