… Dr Kovesdy is a consultant for Abbott Nutrition, Relypsa, Sanofi-Aventis, ZS Pharma, and
Nephrogenex. Dr Morgenstern is a consultant at Arbor Research Collaborative for Health. Dr O’…

Background Health system planning requires careful assessment of chronic kidney disease
(CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-…

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

Importance The established chronic kidney disease (CKD) progression end point of end-stage
renal disease (ESRD) or a doubling of serum creatinine concentration (corresponding to …

The US Renal Data System (USRDS) is the largest and most comprehensive national end-stage
renal disease (ESRD) and chronic kidney disease (CKD) surveillance system in the …

Chronic kidney disease is a progressive condition that affects >10% of the general
population worldwide, amounting to >800 million individuals. Chronic kidney disease is more …

Obesity has become a worldwide epidemic, and its prevalence has been projected to grow
by 40% in the next decade. This increasing prevalence has implications for the risk of …

Background— Patients with chronic kidney disease (stage 5) who undergo hemodialysis
treatment have similarities to heart failure patients in that both populations retain fluid …

In individuals with chronic kidney disease, high dietary phosphorus (P) burden may worsen
hyperparathyroidism and renal osteodystrophy, promote vascular calcification and …

Importance Identifying patients at risk of chronic kidney disease (CKD) progression may
facilitate more optimal nephrology care. Kidney failure risk equations, including such factors as …