User profiles for Curt R. Fischer
Curt FischerOctant Bio Verified email at octant.bio Cited by 4317 |
A metabolomics pipeline for the mechanistic interrogation of the gut microbiome
Gut microorganisms modulate host phenotypes and are associated with numerous health
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …
Selection and optimization of microbial hosts for biofuels production
CR Fischer, D Klein-Marcuschamer… - Metabolic …, 2008 - Elsevier
Currently, the predominant microbially produced biofuel is starch- or sugar-derived ethanol.
However, ethanol is not an ideal fuel molecule, and lignocellulosic feedstocks are …
However, ethanol is not an ideal fuel molecule, and lignocellulosic feedstocks are …
Engineering of Promoter Replacement Cassettes for Fine-Tuning of Gene Expression in Saccharomyces cerevisiae
E Nevoigt, J Kohnke, CR Fischer, H Alper… - Applied and …, 2006 - Am Soc Microbiol
The strong overexpression or complete deletion of a gene gives only limited information
about its control over a certain phenotype or pathway. Gene function studies based on these …
about its control over a certain phenotype or pathway. Gene function studies based on these …
N-hydroxy-pipecolic acid is a mobile metabolite that induces systemic disease resistance in Arabidopsis
…, JG Kim, S Tang, CR Fischer… - Proceedings of the …, 2018 - National Acad Sciences
Systemic acquired resistance (SAR) is a global response in plants induced at the site of
infection that leads to long-lasting and broad-spectrum disease resistance at distal, uninfected …
infection that leads to long-lasting and broad-spectrum disease resistance at distal, uninfected …
Coevolution of Bacteriophage PP01 and Escherichia coli O157:H7 in Continuous Culture
K Mizoguchi, M Morita, CR Fischer… - Applied and …, 2003 - Am Soc Microbiol
The interaction between Escherichia coli O157:H7 and its specific bacteriophage PP01 was
investigated in chemostat continuous culture. Following the addition of bacteriophage PP01, …
investigated in chemostat continuous culture. Following the addition of bacteriophage PP01, …
HEx: A heterologous expression platform for the discovery of fungal natural products
…, M Tang, U Schlecht, J Horecka, CR Fischer… - Science …, 2018 - science.org
For decades, fungi have been a source of US Food and Drug Administration–approved natural
products such as penicillin, cyclosporine, and the statins. Recent breakthroughs in DNA …
products such as penicillin, cyclosporine, and the statins. Recent breakthroughs in DNA …
Depletion of microbiome-derived molecules in the host using Clostridium genetics
…, S Higginbottom, K Nagashima, CR Fischer… - Science, 2019 - science.org
INTRODUCTION The gut microbiota produce hundreds of molecules that are present at
high concentrations in circulation and whose levels vary widely among humans. These …
high concentrations in circulation and whose levels vary widely among humans. These …
[PDF][PDF] Genetic mapping and biochemical basis of yellow feather pigmentation in budgerigars
Parrot feathers contain red, orange, and yellow polyene pigments called psittacofulvins.
Budgerigars are parrots that have been extensively bred for plumage traits during the last …
Budgerigars are parrots that have been extensively bred for plumage traits during the last …
[PDF][PDF] A pathogen-responsive gene cluster for highly modified fatty acids in tomato
JE Jeon, JG Kim, CR Fischer, N Mehta… - Cell, 2020 - cell.com
In response to biotic stress, plants produce suites of highly modified fatty acids that bear
unusual chemical functionalities. Despite their chemical complexity and proposed roles in …
unusual chemical functionalities. Despite their chemical complexity and proposed roles in …
[PDF][PDF] A metabolic pathway for activation of dietary glucosinolates by a human gut symbiont
Consumption of glucosinolates, pro-drug-like metabolites abundant in Brassica vegetables,
has been associated with decreased risk of certain cancers. Gut microbiota have the ability …
has been associated with decreased risk of certain cancers. Gut microbiota have the ability …