Detecting differential growth of microbial populations with Gaussian process regression
PD Tonner, CL Darnell, BE Engelhardt… - Genome …, 2017 - genome.cshlp.org
Microbial growth curves are used to study differential effects of media, genetics, and stress
on microbial population growth. Consequently, many modeling frameworks exist to capture …
on microbial population growth. Consequently, many modeling frameworks exist to capture …
RscS Functions Upstream of SypG To Control the syp Locus and Biofilm Formation in Vibrio fischeri
EA Hussa, CL Darnell, KL Visick - Journal of Bacteriology, 2008 - Am Soc Microbiol
Two-component signal transduction systems, composed of sensor kinase (SK) and response
regulator (RR) proteins, allow bacterial cells to adapt to changes such as environmental …
regulator (RR) proteins, allow bacterial cells to adapt to changes such as environmental …
The Putative Hybrid Sensor Kinase SypF Coordinates Biofilm Formation in Vibrio fischeri by Acting Upstream of Two Response Regulators, SypG and VpsR
CL Darnell, EA Hussa, KL Visick - Journal of Bacteriology, 2008 - Am Soc Microbiol
Colonization of the Hawaiian squid Euprymna scolopes by the marine bacterium Vibrio fischeri
requires the symbiosis polysaccharide (syp) gene cluster, which contributes to symbiotic …
requires the symbiosis polysaccharide (syp) gene cluster, which contributes to symbiotic …
Two-Component Response Regulators of Vibrio fischeri: Identification, Mutagenesis, and Characterization
EA Hussa, TM O'Shea, CL Darnell, EG Ruby… - Journal of …, 2007 - Am Soc Microbiol
Two-component signal transduction systems are utilized by prokaryotic and eukaryotic cells
to sense and respond to environmental stimuli, both to maintain homeostasis and to rapidly …
to sense and respond to environmental stimuli, both to maintain homeostasis and to rapidly …
Inactivation of a novel response regulator is necessary for biofilm formation and host colonization by Vibrio fischeri
AR Morris, CL Darnell, KL Visick - Molecular microbiology, 2011 - Wiley Online Library
The marine bacterium Vibrio fischeri uses a biofilm to promote colonization of its eukaryotic
host Euprymna scolopes. This biofilm depends on the symbiosis polysaccharide (syp) locus, …
host Euprymna scolopes. This biofilm depends on the symbiosis polysaccharide (syp) locus, …
[HTML][HTML] A conserved transcription factor controls gluconeogenesis via distinct targets in hypersaline-adapted archaea with diverse metabolic capabilities
RK Hackley, A Vreugdenhil-Hayslette, CL Darnell… - Plos …, 2024 - journals.plos.org
Timely regulation of carbon metabolic pathways is essential for cellular processes and to
prevent futile cycling of intracellular metabolites. In Halobacterium salinarum, a hypersaline …
prevent futile cycling of intracellular metabolites. In Halobacterium salinarum, a hypersaline …
Transcriptional regulation in archaea: from individual genes to global regulatory networks
…, PD Tonner, CL Darnell… - Annual review of …, 2017 - annualreviews.org
Archaea are major contributors to biogeochemical cycles, possess unique metabolic capabilities,
and resist extreme stress. To regulate the expression of genes encoding these unique …
and resist extreme stress. To regulate the expression of genes encoding these unique …
Draft genome sequence of Myxococcus xanthus wild-type strain DZ2, a model organism for predation and development
S Müller, JW Willett, SM Bahr, CL Darnell… - Genome …, 2013 - Am Soc Microbiol
Myxococcus xanthus is a member of the Myxococcales order within the Deltaproteobacteria
subdivision. The myxobacteria reside in soil, have relatively large genomes, and display …
subdivision. The myxobacteria reside in soil, have relatively large genomes, and display …
The Ribbon-Helix-Helix Domain Protein CdrS Regulates the Tubulin Homolog ftsZ2 To Control Cell Division in Archaea
Precise control of the cell cycle is central to the physiology of all cells. In prior work we
demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms …
demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms …
Systematic discovery of archaeal transcription factor functions in regulatory networks through quantitative phenotyping analysis
CL Darnell, PD Tonner, JG Gulli, SC Schmidler… - …, 2017 - Am Soc Microbiol
Gene regulatory networks (GRNs) are critical for dynamic transcriptional responses to
environmental stress. However, the mechanisms by which GRN regulation adjusts physiology to …
environmental stress. However, the mechanisms by which GRN regulation adjusts physiology to …