User profiles for Dörthe Magdalena Katschinski
 | Dörthe KatschinskiVerified email at med.uni-goettingen.de Cited by 7331 |
[HTML][HTML] Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer
Clinical studies in breast cancer suggest important associations between intratumoral
hypoxia, the upregulation of epidermal growth factor receptor (EGFR or HER1), hypoxia-inducible …
hypoxia, the upregulation of epidermal growth factor receptor (EGFR or HER1), hypoxia-inducible …
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway
Solid tumors often have an inadequate blood supply, which results in large regions that are
subjected to hypoxic or anoxic stress. Hypoxia-inducible factor-1 (HIF-1) is a transcription …
subjected to hypoxic or anoxic stress. Hypoxia-inducible factor-1 (HIF-1) is a transcription …
Knockdown of prolyl‐4‐hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA‐MB‐231 cells by affecting TGF‐β1 processing
…, G Kristiansen, K Farhat, DM Katschinski - … journal of cancer, 2013 - Wiley Online Library
The prolyl‐4‐hydroxylase domain 1–3 (PHD1–3) enzymes are regulating the protein
stability of the α‐subunit of the hypoxia‐inducible factor‐1 (HIF‐1), which mediates oxygen‐…
stability of the α‐subunit of the hypoxia‐inducible factor‐1 (HIF‐1), which mediates oxygen‐…
Epigenetic gene expression links heart failure to memory impairment
…, C Schiffmann, A Zieseniss, DM Katschinski… - EMBO Molecular …, 2021 - embopress.org
In current clinical practice, care of diseased patients is often restricted to separated
disciplines. However, such an organ‐centered approach is not always suitable. For example, …
disciplines. However, such an organ‐centered approach is not always suitable. For example, …
In vivo functions of the prolyl‐4‐hydroxylase domain oxygen sensors: direct route to the treatment of anaemia and the protection of ischaemic tissues
DM Katschinski - Acta physiologica, 2009 - Wiley Online Library
The prolyl‐4‐hydroxylase domain (PHD) 1–3 enzymes have been identified based on their
ability to regulate the stability of hypoxia‐inducible factor α subunits and thus to modify …
ability to regulate the stability of hypoxia‐inducible factor α subunits and thus to modify …
Normoxic destabilization of ATF‐4 depends on proteasomal degradation
M Wottawa, J Koeditz, DM Katschinski - Acta physiologica, 2010 - Wiley Online Library
Aim: Hypoxia‐inducible gene expression is an important physiological adaptive mechanism
in response to a decreased oxygen supply. We have recently described an oxygen‐ and …
in response to a decreased oxygen supply. We have recently described an oxygen‐ and …
CaMKII δ Met281/282 oxidation is not required for recovery of calcium transients during acidosis
…, MJ Baier, S Wagner, DM Katschinski… - American Journal …, 2021 - journals.physiology.org
CaMKII is needed for the recovery of Ca 2+ transients during acidosis but also mediates
postacidic arrhythmias. CaMKIIδ can sustain its activity following Met281/282 oxidation. …
postacidic arrhythmias. CaMKIIδ can sustain its activity following Met281/282 oxidation. …
[CITATION][C] Generation and characterization of glutathione redox potential sensor mice
…, AM Shah, EA Ali, V Nikolaev, DM Katschinski - 2017 - publications.goettingen-research …
[CITATION][C] Remodeling of the actin cytoskeleton in hypoxia: An emerging role for ArhGAP29
…, S Vogel, S Krull, L Swain, DM Katschinski… - 2014 - publications.goettingen-research …
[CITATION][C] The oxygen sensor PHD2 affects cell migration, energy metabolism and mitochondrial function in macrophages
…, J Dudek, AM Shah, DM Katschinski - 2016 - publications.goettingen-research …