User profiles for D. B. Grayden

David Grayden

Dept. of Biomedical Engineering, University of Melbourne
Verified email at unimelb.edu.au
Cited by 6802

Seizure forecasting and cyclic control of seizures

RE Stirling, MJ Cook, DB Grayden, PJ Karoly - Epilepsia, 2021 - Wiley Online Library
… prediction database and competition was launched in 2007 to facilitate comparison between
methods.This heralded a new era of improved metrics and rigorous evaluation of seizure …

High-frequency oscillations in epilepsy: what have we learned and what needs to be addressed

…, MI Maturana, AN Burkitt, MJ Cook, DB Grayden - Neurology, 2021 - AAN Enterprises
For the past 2 decades, high-frequency oscillations (HFOs) have been enthusiastically studied
by the epilepsy community. Emerging evidence shows that HFOs harbor great promise to …

Interictal spikes and epileptic seizures: their relationship and underlying rhythmicity

PJ Karoly, DR Freestone, R Boston, DB Grayden… - Brain, 2016 - academic.oup.com
We report on a quantitative analysis of electrocorticography data from a study that acquired
continuous ambulatory recordings in humans over extended periods of time. The objectives …

Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity

…, SM Davis, AN Burkitt, PJ Mitchell, DB Grayden… - Nature …, 2016 - nature.com
High-fidelity intracranial electrode arrays for recording and stimulating brain activity have
facilitated major advances in the treatment of neurological conditions over the past decade. …

[HTML][HTML] Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human …

…, TJ O'Brien, CN May, J Mocco, DB Grayden… - Journal of …, 2021 - jnis.bmj.com
Background Implantable brain–computer interfaces (BCIs), functioning as motor neuroprostheses,
have the potential to restore voluntary motor impulses to control digital devices and …

Circadian and circaseptan rhythms in human epilepsy: a retrospective cohort study

…, DR Freestone, RE Moss, DB Grayden… - The Lancet …, 2018 - thelancet.com
… Because of recording protocol, seizures reported without onset times were saved at 1 am
in the SeizureTracker database; therefore, we removed all seizures recorded at 1 am. We …

Epilepsyecosystem. org: crowd-sourcing reproducible seizure prediction with long-term human intracranial EEG

…, C Reuben, G Worrell, B Litt, DTJ Liley, DB Grayden… - Brain, 2018 - academic.oup.com
Accurate seizure prediction will transform epilepsy management by offering warnings to
patients or triggering interventions. However, state-of-the-art algorithm design relies on …

The circadian profile of epilepsy improves seizure forecasting

PJ Karoly, H Ung, DB Grayden, L Kuhlmann, K Leyde… - Brain, 2017 - academic.oup.com
It is now established that epilepsy is characterized by periodic dynamics that increase seizure
likelihood at certain times of day, and which are highly patient-specific. However, these …

[HTML][HTML] Critical slowing down as a biomarker for seizure susceptibility

…, K Dell, PJ Karoly, W D'Souza, DB Grayden… - Nature …, 2020 - nature.com
The human brain has the capacity to rapidly change state, and in epilepsy these state
changes can be catastrophic, resulting in loss of consciousness, injury and even death. …

Role of multiple-scale modeling of epilepsy in seizure forecasting

L Kuhlmann, DB Grayden, F Wendling… - Journal of Clinical …, 2015 - journals.lww.com
Over the past three decades, a number of seizure prediction, or forecasting, methods have
been developed. Although major achievements were accomplished regarding the statistical …