Objectives The aims of the present systematic review and meta-analysis were to determine
the relationship between muscular strength and all-cause mortality risk and to examine the …

As with all science, our continually developing concepts of lunar evolution are firmly tied to
both new types of observations and the integration of these observations to the known pool of …

The receptor for advanced glycation end products (RAGE), a multi-ligand member of the
immunoglobulin superfamily of cell surface molecules 1 , 2 , interacts with distinct molecules …

Atrial disease or myopathy forms the substrate for atrial fibrillation (AF) and underlies the
potential for atrial thrombus formation and subsequent stroke. Current diagnostic approaches in …

The ectodomains of numerous proteins are released from cells by proteolysis to yield
soluble intercellular regulators. The responsible protease, tumor necrosis factor-α converting …

Continental crust forms from, and thus chemically depletes, the Earth's mantle. Evidence
that the Earth's mantle was already chemically depleted by melting before the formation of …

We report detailed high precision combined single grain U-Pb and Lu-Hf studies of early
zircons to obtain more reliable indications of the extent of mantle depletion and crustal recycling …

… with numerous reports employing both organ culture and intact animals that administration
of exogenous EGF can stimulate growth of gastrointestinal epithelium (for review see Lee and …

To explore the physiological roles of transforming growth factor a (TGFa), we disrupted the
mouse gene by homologous recombination in embryonic stem cells. Homoxygous mutant …

Background— Previous studies suggested that blockade of RAGE in diabetic apolipoprotein
(apo) E–null mice suppressed early acceleration of atherosclerosis. A critical test of the …