User profiles for D. D. Kang

Dongwan Don Kang

- Verified email at gilead.com - Cited by 6490

Dongyeon Daniel Kang

- Verified email at kist.re.kr - Cited by 335

Diana D. Kang

- Verified email at osu.edu - Cited by 291

[HTML][HTML] MetaBAT 2: an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies

DD Kang, F Li, E Kirton, A Thomas, R Egan, H An… - PeerJ, 2019 - peerj.com
We previously reported on MetaBAT, an automated metagenome binning software tool to
reconstruct single genomes from microbial communities for subsequent analyses of …

[HTML][HTML] MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities

DD Kang, J Froula, R Egan, Z Wang - PeerJ, 2015 - peerj.com
Grouping large genomic fragments assembled from shotgun metagenomic sequences to
deconvolute complex microbial communities, or metagenome binning, enables the study of …

Delivery of CRISPR-Cas9 system for screening and editing RNA binding proteins in cancer

J Yan, DD Kang, G Turnbull, Y Dong - Advanced drug delivery reviews, 2022 - Elsevier
RNA-binding proteins (RBPs) play an important role in RNA metabolism, regulating the stability,
localization, and functional dynamics of RNAs. Alternation in the RBP-RNA network has …

[HTML][HTML] The epigenomic landscape of prokaryotes

…, A Fomenkov, R Fries, J Froula, DD Kang… - PLoS …, 2016 - journals.plos.org
DNA methylation acts in concert with restriction enzymes to protect the integrity of prokaryotic
genomes. Studies in a limited number of organisms suggest that methylation also …

Intratumoral delivery of IL-12 and IL-27 mRNA using lipid nanoparticles for cancer immunotherapy

…, K Lynch, W Zhao, X Hou, S Du, DD Kang… - Journal of Controlled …, 2022 - Elsevier
Cytokines are important immunotherapeutics with approved drugs for the treatment of human
cancers. However, systemic administration of cytokines often fails to achieve adequate …

Harnessing lipid nanoparticles for efficient CRISPR delivery

J Yan, DD Kang, Y Dong - Biomaterials Science, 2021 - pubs.rsc.org
The CRISPR-Cas system has revolutionized the biomedical research field with its simple and
flexible genome editing method. In October 2020, Emmanuelle Charpentier and Jennifer A…

An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection

X Wang, DD Kang, K Shen, C Song, S Lu… - …, 2012 - academic.oup.com
With the rapid advances and prevalence of high-throughput genomic technologies, integrating
information of multiple relevant genomic studies has brought new challenges. Microarray …

[HTML][HTML] Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy

…, B Deng, DW McComb, Y Zhang, DD Kang… - Nature …, 2021 - nature.com
Antibodies targeting costimulatory receptors of T cells have been developed for the activation
of T cell immunity in cancer immunotherapy. However, costimulatory molecule expression …

STING agonist-derived LNP-mRNA vaccine enhances protective immunity against SARS-CoV-2

Y Zhang, J Yan, X Hou, C Wang, DD Kang, Y Xue… - Nano Letters, 2023 - ACS Publications
Lipid nanoparticle (LNP)-mediated delivery of messenger RNA (mRNA) COVID-19 vaccines
has provided large-scale immune protection to the public. To elicit a robust immune …

[HTML][HTML] Profiling early lung immune responses in the mouse model of tuberculosis

DD Kang, Y Lin, JR Moreno, TD Randall, SA Khader - PloS one, 2011 - journals.plos.org
Tuberculosis (TB) is caused by the intracellular bacteria Mycobacterium tuberculosis, and
kills more than 1.5 million people every year worldwide. Immunity to TB is associated with the …