We investigated the appearance and progression of disease-relevant signs in the B6.Htt
Q111/+ mouse, a genetically precise model of the mutation that causes Huntington’s disease (…

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease whose
predominant neuropathological signature is the selective loss of medium spiny neurons in the …

… & Calder 1979), the second in the middle of a continent (the site at Manaus) (Shuttleworth
1988). A comparison is here made against potential evaporation rate as estimated from the …

Apathy is one of the most prevalent and progressive psychiatric symptoms in Huntington’s
disease (HD) patients. However, preclinical work in HD mouse models tends to focus on …

In the spirit of the Special Issue of HESS to which it contributes, this paper documents the
origin and development of the science of natural evaporation from land surfaces over the last …

… Shuttleworth (1976b) demonstrated that it is possible to write a ‘multi-layer’ model of the …
with published data in partially wet conditions (Shuttleworth, 1976a). This version allows a …

… We then present a parallel computational study that examines the performance of these
methods and compares them to an additive Schwarz domain decomposition (DD) algorithm. …

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease whose
neuropathological signature is a selective loss of medium spiny neurons in the striatum. …

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease whose
neuropathological signature is a selective loss of medium spiny neurons in the striatum. …

… In 1842 he married an heiress with good expectations, Janet Shuttleworth, of Gawthorpe
Hall, Lancashire, and on his marriage assumed the name of Kay-Shuttleworth. He was knighted …