Digital pathology and the adoption of image analysis have grown rapidly in the last few years.
This is largely due to the implementation of whole slide scanning, advances in software …

QuPath is new bioimage analysis software designed to meet the growing need for a user-friendly,
extensible, open-source solution for digital pathology and whole slide image analysis. …

The treatment of cancer is becoming more precise, targeting specific oncogenic drivers with
targeted molecular therapies. The epidermal growth factor receptor has been found to be …

Purpose: A number of independent gene expression profiling studies have identified
transcriptional subtypes in colorectal cancer with potential diagnostic utility, culminating in …

Purpose: EphA2, a member of the Eph receptor tyrosine kinases family, is an important
regulator of tumor initiation, neovascularization, and metastasis in a wide range of epithelial and …

Next Generation Sequencing (NGS) has the potential of becoming an important tool in clinical
diagnosis and therapeutic decision-making in oncology owing to its enhanced sensitivity …

Digital image analysis (DIA) is becoming central to the quantitative evaluation of tissue
biomarkers for discovery, diagnosis and therapeutic selection for the delivery of precision …

Purpose: Despite the use of 5-fluorouracil (5-FU)–based adjuvant treatments, a large
proportion of patients with high-risk stage II/III colorectal cancer will relapse. Thus, novel …

Stromal-derived intratumoural heterogeneity (ITH) has been shown to undermine molecular
stratification of patients into appropriate prognostic/predictive subgroups. Here, using …

Background Radiotherapy is an effective treatment of intermediate/high-risk locally advanced
prostate cancer, however, >30% of patients relapse within 5 years. Clinicopathological …