Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was …

Malignant brain tumors strike deep into the psyche of those receiving and those delivering
the diagnosis. Malignant gliomas, the most common subtype of primary brain tumors, are …

Despite decades of research, brain tumours remain among the deadliest of all forms of cancer.
The ability of these tumours to resist almost all conventional and novel treatments relates, …

Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease,
but their role is poorly understood. Here we show that a subtype of reactive astrocytes, …

Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …

… DH participated in project coordination and SHANK3 genomic conservation analysis. AKM,
RPN, TW and JFC coordinated the project, wrote the manuscript and incorporated revisions …

During early human pregnancy the uterine mucosa transforms into the decidua, into which
the fetal placenta implants and where placental trophoblast cells intermingle and …

Neural crest cells are multipotential stem cells that contribute extensively to vertebrate
development and give rise to various cell and tissue types. Determination of the fate of …

The ability to generate specific genetic modifications in mice provides a powerful approach
to assess gene function. When genetic modifications have been generated in the germ line, …

A subpopulation of neural crest termed the cardiac neural crest is required in avian embryos
to initiate reorganization of the outflow tract of the developing cardiovascular system. In …