Drug therapies and delivery mechanisms to treat perturbed skin wound healing

JS Chin, L Madden, SY Chew, DL Becker - Advanced Drug Delivery …, 2019 - Elsevier
Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control of …

Controlled release of drugs in electrosprayed nanoparticles for bone tissue engineering

…, C Gandhimathi, JR Venugopal, DL Becker… - Advanced Drug Delivery …, 2015 - Elsevier
Generating porous topographic substrates, by mimicking the native extracellular matrix (ECM)
to promote the regeneration of damaged bone tissues, is a challenging process. Generally…

[HTML][HTML] The pathogenesis of tendon microdamage in athletes: the horse as a natural model for basic cellular research

JC Patterson-Kane, DL Becker, T Rich - Journal of comparative pathology, 2012 - Elsevier
The equine superficial digital flexor tendon (SDFT) is a frequently injured structure that is
functionally and clinically equivalent to the human Achilles tendon (AT). Both act as critical …

[PDF][PDF] Targeting connexin43 expression accelerates the rate of wound repair

…, S Franke, L Law, P Martin, CR Green, DL Becker - Current Biology, 2003 - cell.com
The repair of tissue damage is a key survival process in all organisms and involves the
coordinated activation of several cell types. Cell-cell communication is clearly fundamental to this …

A flexible multiplexed immunosensor for point-of-care in situ wound monitoring

…, I Abdelwahab, KP Loh, CH Chen, DL Becker… - Science …, 2021 - science.org
Chronic wounds arise from interruption of normal healing due to many potential pathophysiological
factors. Monitoring these multivariate factors can provide personalized diagnostic …

Battery-free and AI-enabled multiplexed sensor patches for wound monitoring

…, Y Yu, NABM Salleh, JS Chin, Z Xiong, DL Becker… - Science …, 2023 - science.org
Wound healing is a dynamic process with multiple phases. Rapid profiling and quantitative
characterization of inflammation and infection remain challenging. We report a paper-like …

Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration

…, CM Wang, P Martin, DL Becker - Journal of cell …, 2006 - journals.biologists.com
Becker; Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory
response, enhanced keratinocyte proliferation and wound fibroblast migration. J Cell Sci …

Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury

…, PN Anderson, JE Cook, CR Green, DL Becker - Molecular and Cellular …, 2008 - Elsevier
After traumatic CNS injury, a cascade of secondary events expands the initial lesion. The
gap-junction protein connexin43 (Cx43), which is transiently up-regulated, has been implicated …

Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitro

…, D Ciantar, J Stark, DL Becker… - Biology of …, 2005 - academic.oup.com
Follicle-Stimulating Hormone (FSH) at a wide range of doses is routinely added to culture
media during in vitro maturation (IVM) of oocytes, but the effects on oocyte health are unclear. …

[PDF][PDF] Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections

…, C Thrasivoulou, C Ekwobi, DL Becker - Biophysical journal, 2006 - cell.com
We performed second harmonic generation (SHG) imaging of collagen in rat-tendon
cryosections, using femtosecond laser scanning confocal microscopy, both in backscattering and …