[HTML][HTML] Cytoplasmic dynein as a facilitator of nuclear envelope breakdown
During prophase in higher cells, centrosomes localize to deep invaginations in the nuclear
envelope in a microtubule-dependent process. Loss of nuclear membranes in prometaphase …
envelope in a microtubule-dependent process. Loss of nuclear membranes in prometaphase …
Dynactin is required for microtubule anchoring at centrosomes
The multiprotein complex, dynactin, is an integral part of the cytoplasmic dynein motor and
is required for dynein-based motility in vitro and in vivo. In living cells, perturbation of the …
is required for dynein-based motility in vitro and in vivo. In living cells, perturbation of the …
WND-CHARM: Multi-purpose image classification using compound image transforms
We describe a multi-purpose image classifier that can be applied to a wide variety of image
classification tasks without modifications or fine-tuning, and yet provide classification …
classification tasks without modifications or fine-tuning, and yet provide classification …
[HTML][HTML] Pattern recognition software and techniques for biological image analysis
The increasing prevalence of automated image acquisition systems is enabling new types of
microscopy experiments that generate large image datasets. However, there is a perceived …
microscopy experiments that generate large image datasets. However, there is a perceived …
[HTML][HTML] Wndchrm–an open source utility for biological image analysis
Background Biological imaging is an emerging field, covering a wide range of applications
in biological and clinical research. However, while machinery for automated experimenting …
in biological and clinical research. However, while machinery for automated experimenting …
Knee x-ray image analysis method for automated detection of osteoarthritis
We describe a method for automated detection of radiographic osteoarthritis (OA) in knee X-ray
images. The detection is based on the Kellgren-Lawrence (KL) classification grades, …
images. The detection is based on the Kellgren-Lawrence (KL) classification grades, …
Impressionism, expressionism, surrealism: Automated recognition of painters and schools of art
We describe a method for automated recognition of painters and schools of art based on their
signature styles and studied the computer-based perception of visual art. Paintings of nine …
signature styles and studied the computer-based perception of visual art. Paintings of nine …
Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and …
…, E Raborn, R Wan, MR Mughal, DM Eckley… - Journal of …, 2010 - Soc Neuroscience
The subependymal zone (SEZ) of the lateral ventricles is one of the areas of the adult brain
where new neurons are continuously generated from neural stem cells (NSCs), via rapidly …
where new neurons are continuously generated from neural stem cells (NSCs), via rapidly …
[HTML][HTML] Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
…, K Marosi, MA Wilson, WB Iser, DM Eckley… - Scientific reports, 2017 - nature.com
Aging is a major international concern that brings formidable socioeconomic and healthcare
challenges. Small molecules capable of improving the health of older individuals are being …
challenges. Small molecules capable of improving the health of older individuals are being …
Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end
The multisubunit protein, dynactin, is a critical component of the cytoplasmic dynein motor
machinery. Dynactin contains two distinct structural domains: a projecting sidearm that …
machinery. Dynactin contains two distinct structural domains: a projecting sidearm that …