User profiles for D. M. Howard

David M Howard

- Verified email at kcl.ac.uk - Cited by 6624

David M Howard

- Verified email at rhul.ac.uk - Cited by 4161

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

DM Howard, MJ Adams, TK Clarke, JD Hafferty… - Nature …, 2019 - nature.com
Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …

Relationships between CO~ 2 evolution, moisture content and temperature for a range of soil types

DM Howard, PJA Howard - Soil Biology and Biochemistry, 1993 - Elsevier
Soils were collected from two locations at six sites on each of eight soil types. After sieving,
soil CO 2 evolution was measured at three moisture contents and at 5, 10, 15 and 20C. Our …

[HTML][HTML] Attributes of excellent attending-physician role models

…, DE Kern, K Kolodner, DM Howard… - … England Journal of …, 1998 - Mass Medical Soc
Background Although effective role models are important in medical education, little is known
about the characteristics of physicians who serve as excellent clinical role models. We …

Endemic melioidosis in tropical northern Australia: a 10-year prospective study and review of the literature

BJ Currie, DA Fisher, DM Howard… - Clinical Infectious …, 2000 - academic.oup.com
In a prospective study of melioidosis in northern Australia, 252 cases were found over 10
years. Of these, 46% were bacteremic, and 49 (19%) patients died. Despite administration of …

[HTML][HTML] Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

DM Howard, MJ Adams, M Shirali, TK Clarke… - Nature …, 2018 - nature.com
Depression is a polygenic trait that causes extensive periods of disability. Previous genetic
studies have identified common risk variants which have progressively increased in number …

[HTML][HTML] Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N= 112 117)

TK Clarke, MJ Adams, G Davies, DM Howard… - Molecular …, 2017 - nature.com
Alcohol consumption has been linked to over 200 diseases and is responsible for over 5%
of the global disease burden. Well-known genetic variants in alcohol metabolizing genes, for …

Use of organic carbon and loss-on-ignition to estimate soil organic matter in different soil types and horizons

PJA Howard, DM Howard - Biology and Fertility of soils, 1990 - Springer
Loss-on-ignition (LOI) and the organic C content have been used to estimate soil organic
matter. Organic matter is often estimated from organic C by applying a factor of 1.724. Several …

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

…, C Fawns-Ritchie, MJ Adams, DM Howard… - Nature …, 2018 - nature.com
Neuroticism is a relatively stable personality trait characterized by negative emotionality (for
example, worry and guilt) 1 ; heritability estimated from twin studies ranges from 30 to 50% 2 …

The epidemiology of melioidosis in Australia and Papua New Guinea

BJ Currie, DA Fisher, DM Howard, JNC Burrow… - Acta tropica, 2000 - Elsevier
Melioidosis was first described in Australia in an outbreak in sheep in 1949 in north
Queensland (22S). Human melioidosis was first described from Townsville (19S) in 1950. …

Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts

…, MJ Adams, DM Howard… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Alcohol use disorders are common conditions that have enormous social and
economic consequences. Genome-wide association analyses were performed to identify …