Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca2+/Calmodulin-dependent protein kinase II
…, M Sahores, D Anane, DM Lopes… - Proceedings of the …, 2011 - National Acad Sciences
The balance between excitatory and inhibitory synapses is crucial for normal brain function.
Wnt proteins stimulate synapse formation by increasing synaptic assembly. However, it is …
Wnt proteins stimulate synapse formation by increasing synaptic assembly. However, it is …
[PDF][PDF] Persistent alterations in microglial enhancers in a model of chronic pain
Chronic pain is a common and devastating condition that induces well-characterized changes
in neurons and microglia. One major unanswered question is why these changes should …
in neurons and microglia. One major unanswered question is why these changes should …
[HTML][HTML] The molecular fingerprint of dorsal root and trigeminal ganglion neurons
The dorsal root ganglia (DRG) and trigeminal ganglia (TG) are clusters of cell bodies of
highly specialized sensory neurons which are responsible for relaying information about our …
highly specialized sensory neurons which are responsible for relaying information about our …
[HTML][HTML] Sex differences in peripheral not central immune responses to pain-inducing injury
Women suffer chronic pain more frequently than men. It is not clear whether this is due to
differences in higher level cognitive processes or basic nociceptive responses. In this study we …
differences in higher level cognitive processes or basic nociceptive responses. In this study we …
Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer
J Alter, CA Sennoga, DM Lopes, RJ Eckersley… - Ultrasound in medicine …, 2009 - Elsevier
In the search for an efficient nonviral gene therapy approach for the treatment of genetic
disorders of cardiac and skeletal muscle such as Duchenne muscular dystrophy, ultrasound in …
disorders of cardiac and skeletal muscle such as Duchenne muscular dystrophy, ultrasound in …
Ultraviolet radiation on the skin: a painful experience?
DM Lopes, SB McMahon - CNS neuroscience & therapeutics, 2016 - Wiley Online Library
Excessive exposure of skin to ultraviolet radiation ( UVR ) has dramatic clinical effects in
humans, and it is a significant public health concern. Discomfort and sensory changes caused …
humans, and it is a significant public health concern. Discomfort and sensory changes caused …
[HTML][HTML] Deficient Wnt signalling triggers striatal synaptic degeneration and impaired motor behaviour in adult mice
Synapse degeneration is an early and invariant feature of neurodegenerative diseases.
Indeed, synapse loss occurs prior to neuronal degeneration and correlates with the symptom …
Indeed, synapse loss occurs prior to neuronal degeneration and correlates with the symptom …
Use of recombinant granulocyte-macrophage colony stimulating factor in the Brazil radiation accident
A Butturini, RP Gale, DM Lopes, CB Cunha, WG Ho… - The Lancet, 1988 - Elsevier
8 patients with bone marrow failure after a caesium-137 radiation accident were treated with
recombinant human granulocyte-macrophage colony stimulating factor (rHuGM-CSF). The …
recombinant human granulocyte-macrophage colony stimulating factor (rHuGM-CSF). The …
[HTML][HTML] Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
DM Lopes, SK Llewellyn, IF Harrison - Translational Neurodegeneration, 2022 - Springer
Many neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease,
are characterised by the accumulation of misfolded protein deposits in the brain, leading to …
are characterised by the accumulation of misfolded protein deposits in the brain, leading to …
Large scale in vivo recording of sensory neuron activity with GCaMP6
Greater emphasis on the study of intact cellular networks in their physiological environment
has led to rapid advances in intravital imaging of the central nervous system (CNS), while the …
has led to rapid advances in intravital imaging of the central nervous system (CNS), while the …