… (Citation52), our own unpublished data suggest that p38α in myeloid cells does in fact play
an important role in EAE pathogenesis (DN Krementsov, R. Noubade, JA Dragon, K. Otsu, M. …

Specific spatial arrangements of proteins and lipids are central to the coordination of many
biological processes. Tetraspanins have been proposed to laterally organize cellular …

… Krementsov … DN Krementsov and EB Krementsova contributed equally to this paper. …
DN Krementsov and EB Krementsova contributed equally to this paper. …

… specifically in T cells to EAE susceptibility, we used dn-p38-Tg mice where p38 MAPK activity
is markedly and selectively inhibited in T cells. Because the dn-p38-Tg mice are on the B10…

Background Dysregulation of gut microbiota-associated tryptophan metabolism has been
observed in patients with multiple sclerosis. However, defining direct mechanistic links …

… Cells from a patient suffering from hyper–immunoglobulin E (IgE) syndrome and carrying a
heterozygous dominant-negative (DN) mutation of STAT3 (STAT3-DN) had a normal pattern …

Understanding the DNA elements that constitute and control the regulatory genome is
critical for the appropriate therapeutic management of complex diseases. Here, using …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. The etiology
of MS is multifactorial, with disease risk determined by genetics and environmental factors. …

Background The presence of the tetraspanins CD9, CD63, CD81 and CD82 at HIV-1 budding
sites, at the virological synapse (VS), and their enrichment in HIV-1 virions has been well-…

Partitioning of membrane proteins into various types of microdomains is crucial for many
cellular functions. Tetraspanin‐enriched microdomains (TEMs) are a unique type of protein‐…