User profiles for D. P. Bendixsen

Devin P Bendixsen

Staff Bioinformatician, MRC Human Genetics Unit, University of Edinburgh
Verified email at ed.ac.uk
Cited by 431

Saccharomyces yeast hybrids on the rise

DP Bendixsen, JG Frazao, R Stelkens - Yeast, 2022 - Wiley Online Library
Saccharomyces hybrid yeasts are receiving increasing attention as a powerful model
system to understand adaptation to environmental stress and speciation mechanisms, using …

Forest and woodland replacement patterns following drought-related mortality

…, E Aynekulu, DP Bendixsen… - Proceedings of the …, 2020 - National Acad Sciences
Forest vulnerability to drought is expected to increase under anthropogenic climate change,
and drought-induced mortality and community dynamics following drought have major …

Negative epistasis in experimental RNA fitness landscapes

DP Bendixsen, B Østman, EJ Hayden - Journal of molecular evolution, 2017 - Springer
Mutations and their effects on fitness are a fundamental component of evolution. The effects
of some mutations change in the presence of other mutations, and this is referred to as …

[HTML][HTML] The evolutionary and ecological potential of yeast hybrids

R Stelkens, DP Bendixsen - Current Opinion in Genetics & Development, 2022 - Elsevier
Recent findings in yeast genetics and genomics have advanced our understanding of the
evolutionary potential unlocked by hybridization, especially in the genus Saccharomyces. We …

Stress factors associated with forest decline in xeric oak forests of south-central United States

DP Bendixsen, SW Hallgren, AE Frazier - Forest Ecology and Management, 2015 - Elsevier
Near total canopy mortality occurred over several tens of hectares of post oak-blackjack oak
forests in the Cross Timbers of south-central United States in 2008. This event closely …

[PDF][PDF] The dynamics of adaptation to stress from standing genetic variation and de novo mutations

…, C Gilchrist, A Rêgo, DP Bendixsen… - Molecular biology …, 2022 - academic.oup.com
Adaptation from standing genetic variation is an important process underlying evolution in
natural populations, but we rarely get the opportunity to observe the dynamics of fitness and …

Genomic Evidence of an Ancient East Asian Divergence Event in Wild Saccharomyces cerevisiae

DP Bendixsen, N Gettle, C Gilchrist… - Genome Biology and …, 2021 - academic.oup.com
Comparative genome analyses have suggested East Asia to be the cradle of the domesticated
microbe Brewer’s yeast (Saccharomyces cerevisiae), used in the food and biotechnology …

Recombining your way out of trouble: the genetic architecture of hybrid fitness under environmental stress

Z Zhang, DP Bendixsen, T Janzen… - Molecular biology …, 2020 - academic.oup.com
Hybridization between species can either promote or impede adaptation. But we know very
little about the genetic basis of hybrid fitness, especially in nondomesticated organisms, and …

Experimental resurrection of ancestral mammalian CPEB3 ribozymes reveals deep functional conservation

DP Bendixsen, TB Pollock, G Peri… - Molecular Biology and …, 2021 - academic.oup.com
Self-cleaving ribozymes are genetic elements found in all domains of life, but their evolution
remains poorly understood. A ribozyme located in the second intron of the cytoplasmic …

[HTML][HTML] Genotype network intersections promote evolutionary innovation

DP Bendixsen, J Collet, B Østman, EJ Hayden - PLoS biology, 2019 - journals.plos.org
Evolutionary innovations are qualitatively novel traits that emerge through evolution and
increase biodiversity. The genetic mechanisms of innovation remain poorly understood. A …