Many chronic human diseases, including multiple neurodegenerative diseases, are
associated with deleterious protein aggregates, also called protein amyloids. One common …

The pathogenic aggregation of the amyloid β-peptide (Aβ) is considered a hallmark of the
progression of Alzheimer’s disease, the leading cause of senile dementia in the elderly and …

Microbial cell factories (MCFs) are of considerable interest to convert low value renewable
substrates to biofuels and high value chemicals. This review highlights the progress of …

Amyloid fibrils represent a stable form of many misfolded proteins associated with
numerous diseases. Among these are Parkinson’s disease (α-synuclein), Type II diabetes (islet …

GridMAT‐MD is a new program developed to aid in the analysis of lipid bilayers from molecular
dynamics simulations. It reads a GROMACS coordinate file and generates two types of …

Molecular dynamics simulations are being applied to increasingly complex systems, including
those involving small endogenous compounds and drug molecules. In order to obtain …

The mechanism and the site of substrate (ie, aglycone) recognition and specificity were
investigated in maize β-glucosidase (Glu1) by x-ray crystallography by using crystals of a …

… We thank Peter Bowerman and Dr. Brenda SJ Winkel for stimulating discussions on
flavonoid chemistry, William J. Allen for useful discussions during the development of morin …

Terpene volatiles play important roles in plant-organism interactions as attractants of pollinators
or as defense compounds against herbivores. Among the most common plant volatiles …

Abscisic acid (ABA) has shown efficacy in the treatment of diabetes and inflammation;
however, its molecular targets and the mechanisms of action underlying its immunomodulatory …