User profiles for D. R. Velez Edwards

Digna R Velez Edwards

Vanderbilt University
Verified email at vanderbilt.edu
Cited by 13574

Population stratification in genetic association studies

…, X Gao, DR Velez Edwards, TL Edwards - Current protocols in …, 2017 - Wiley Online Library
Population stratification (PS) is a primary consideration in studies of genetic determinants of
human traits. Failure to control for PS may lead to confounding, causing a study to fail for …

Alcohol use in pregnancy and miscarriage: a systematic review and meta‐analysis

…, LA Lam, SH Jones, DR Velez Edwards… - Alcoholism: Clinical …, 2019 - Wiley Online Library
To systematically review and critically evaluate studies reporting alcohol exposure during
pregnancy and miscarriage. We searched PubMed, EMBASE, PsycINFO, and ProQuest …

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

…, E Tzanis, JN Hellwege, A Giri, DR Velez Edwards… - Nature …, 2018 - nature.com
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

…, DC Whiteman, LC Giudice, DR Velez-Edwards… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

…, PWF Wilson, PS Tsao, DR Velez Edwards… - Nature …, 2019 - nature.com
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood
pressure to identify genes, tissues, phenomes and medication contexts of blood pressure …

[HTML][HTML] Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

…, J Yang, DR Velez Edwards… - Nature …, 2017 - nature.com
Endometriosis is a heritable hormone-dependent gynecological disorder, associated with
severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely …

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

…, T Edwards, D Ruderfer, DR Velez Edwards… - Science, 2018 - science.org
Genetic association studies often examine features independently, potentially missing
subpopulations with multiple phenotypes that share a single cause. We describe an approach that …

Toll-like receptor 1 polymorphisms increase susceptibility to candidemia

…, E Van De Vosse, DR Velez Edwards… - Journal of Infectious …, 2012 - academic.oup.com
(See the editorial commentary by Bagni and Whitby, on pages 873–4 .) Background.
Candidemia is a severe invasive fungal infection with high mortality. Recognition of Candida …

Risk of miscarriage among black women and white women in a US prospective cohort study

S Mukherjee, DR Velez Edwards… - American journal of …, 2013 - academic.oup.com
Many adverse pregnancy outcomes differ by race. We examined the association between
self-reported race and miscarriage (pregnancy loss at <20 weeks) in a community-based …

Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene)

…, RA Dubin, L Bertram, DR Velez Edwards… - Public health …, 2010 - karger.com
Aim: Our goal wasto produce a field synopsis of genetic associations with preterm birth and
to set up a publicly available online database summarizing the data. Methods: We performed …