Specialized oxygen-sensing cells in the nervous system generate rapid behavioural responses
to oxygen. We show here that the nematode Caenorhabditis elegans exhibits a strong …

Background Identifying individuals at risk for developing Alzheimer disease (AD) is of utmost
importance. Although genetic studies have identified AD-associated SNPs in APOE and …

Purpose: To use structural magnetic resonance (MR) images to identify a pattern of regional
atrophy characteristic of mild Alzheimer disease (AD) and to investigate whether presence …

Soluble guanylate cyclases are nitric oxide-responsive signaling proteins in which the nitric
oxide sensor is a heme-binding domain of unknown structure that we have termed the heme-…

Homeostatic sensory systems detect small deviations in temperature, water balance, pH, and
energy needs to regulate adaptive behavior and physiology. In C. elegans, a homeostatic …

The nematode Caenorhabditis elegans has complex, naturally variable behavioral responses
to environmental oxygen, food, and other animals. C. elegans detects oxygen through …

Restriction spectrum imaging (RSI) is a novel diffusion‐weighted MRI technique that uses
the mathematically distinct behavior of water diffusion in separable microscopic tissue …

Noninvasive MRI biomarkers for Alzheimer's disease (AD) may enable earlier clinical
diagnosis and the monitoring of therapeutic effectiveness. To assess potential neuroimaging …

Soluble guanylate cyclase (sGC) is a nitric oxide- (NO-) sensing hemoprotein that has been
found in eukaryotes from Drosophila to humans. Prokaryotic proteins with significant …

Objectives To develop and validate a genetic tool to predict age of onset of aggressive prostate
cancer (PCa) and to guide decisions of who to screen and at what age. Design Analysis …