The Lotka-Volterra (LV) model was introduced in the early 20th Century to describe predator-prey
systems. Since then, the model has been expanded to capture the dynamics of …

Background Human, animal, and environmental health are increasingly threatened by the
emergence and spread of antibiotic resistance. Inappropriate use of antibiotic treatments …

Cystic fibrosis (CF) is widely known as a disease of the lung, even though it is in truth a
systemic disease, whose symptoms typically manifest in gastrointestinal dysfunction first. CF …

For close to a century, Lotka-Volterra (LV) models have been used to investigate interactions
among populations of different species. For a few species, these investigations are …

Phosphoinositides are signalling lipids that constitute a complex network regulating many
cellular processes. We propose a computational model that accounts for all species of …

As artificial intelligence research advances, the platforms used to evaluate AI agents need
to adapt and grow to continue to challenge them. We present the Polycraft World AI Lab (PAL)…

Almost every biomedical systems analysis requires early decisions regarding the choice of
the most suitable representations to be used. De facto the most prevalent choice is a system …

The lung epithelium is lined with a layer of airway surface liquid (ASL) that is crucial for
healthy lung function. ASL thickness is controlled by two ion channels: epithelium sodium …

Networks are ubiquitous throughout biology, spanning the entire range from molecules to
food webs and global environmental systems. Yet, despite substantial efforts by the scientific …

Lotka-Volterra (LV) and Multivariate Autoregressive (MAR) models are computational
frameworks with different mathematical structures that have both been proposed for the same …