User profiles for D. W. Lambert
Daniel W LambertUniversity of Sheffield Verified email at sheffield.ac.uk Cited by 4651 |
Challenges and directions in studying cell–cell communication by extracellular vesicles
Extracellular vesicles (EVs) are increasingly recognized as important mediators of intercellular
communication. They have important roles in numerous physiological and pathological …
communication. They have important roles in numerous physiological and pathological …
Membrane-associated zinc peptidase families: comparing ACE and ACE2
JL Guy, DW Lambert, FJ Warner, NM Hooper… - … et Biophysica Acta (BBA …, 2005 - Elsevier
… has been detected in urine (DW Lambert, GI Rice, NM Hooper and … is distinct from that of
ACE (DW Lambert, NM Hooper and AJ … and cytosolic domains (DW Lambert, K. Pogson and AJ …
ACE (DW Lambert, NM Hooper and AJ … and cytosolic domains (DW Lambert, K. Pogson and AJ …
Angiotensin-converting enzyme 2 and new insights into the renin–angiotensin system
DW Lambert, NM Hooper, AJ Turner - Biochemical pharmacology, 2008 - Elsevier
Components of the renin–angiotensin system are well established targets for pharmacological
intervention in a variety of disorders. Many such therapies abrogate the effects of the …
intervention in a variety of disorders. Many such therapies abrogate the effects of the …
[HTML][HTML] Tumor necrosis factor-α convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) …
DW Lambert, M Yarski, FJ Warner, P Thornhill… - Journal of Biological …, 2005 - ASBMB
Angiotensin-converting enzyme-2 (ACE2) is a critical regulator of heart function and a cellular
receptor for the causative agent of severe-acute respiratory syndrome (SARS), SARS-CoV …
receptor for the causative agent of severe-acute respiratory syndrome (SARS), SARS-CoV …
Substrate‐induced regulation of the human colonic monocarboxylate transporter, MCT1
MA Cuff, DW Lambert… - The Journal of …, 2002 - Wiley Online Library
Butyrate is the principal source of energy for colonic epithelial cells, and has profound
effects on their proliferation, differentiation and apoptosis. Transport of butyrate across the …
effects on their proliferation, differentiation and apoptosis. Transport of butyrate across the …
[HTML][HTML] Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells
FJ Warner, RA Lew, AI Smith, DW Lambert… - Journal of Biological …, 2005 - ASBMB
Angiotensin-converting enzyme-2 (ACE2) is a homologue of angiotensin-I converting enzyme
(ACE), the central enzyme of the renin-angiotensin system (RAS). ACE2 is abundant in …
(ACE), the central enzyme of the renin-angiotensin system (RAS). ACE2 is abundant in …
[HTML][HTML] MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1
…, AV Jones, EE Hinsley, SA Whawell, DW Lambert - FEBS letters, 2011 - Elsevier
Alterations in the levels of molecules which interact with the extracellular matrix, such as
integrins, are associated with invasion of oral squamous cell carcinomas (OSCC). The …
integrins, are associated with invasion of oral squamous cell carcinomas (OSCC). The …
Epigenetic regulation of angiotensin-converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress
NE Clarke, ND Belyaev, DW Lambert… - Clinical Science, 2014 - portlandpress.com
ACE2 (angiotensin-converting enzyme 2) counterbalances the actions of ACE (angiotensin-converting
enzyme) by metabolizing its catalytic product, the vasoactive and fibrogenic …
enzyme) by metabolizing its catalytic product, the vasoactive and fibrogenic …
[HTML][HTML] Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain
DW Lambert, NE Clarke, NM Hooper, AJ Turner - FEBS letters, 2008 - Elsevier
Angiotensin-converting enzyme-2 (ACE2) is a regulatory protein of the renin–angiotensin
system (RAS) and a receptor for the causative agent of severe-acute respiratory syndrome (…
system (RAS) and a receptor for the causative agent of severe-acute respiratory syndrome (…
[HTML][HTML] Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy
DW Lambert, IS Wood, A Ellis… - British journal of …, 2002 - nature.com
Healthy colonocytes derive 60–70% of their energy supply from short-chain fatty acids,
particularly butyrate. Butyrate has profound effects on differentiation, proliferation and apoptosis …
particularly butyrate. Butyrate has profound effects on differentiation, proliferation and apoptosis …