Conventional chemotherapy regimens for the treatment of advanced Kaposi’s sarcoma (KS)
show limited efficacy and considerable toxicity. Liposomal anthracyclines with potential …

Trastuzumab, a drug targeting human epidermal growth factor receptor 2, improves survival
rate in women with metastatic breast cancer. Symptomatic heart failure, a serious adverse …

PURPOSE Kaposi's sarcoma (KS), the most common neoplasm in patients with AIDS, is a
significant clinical problem for which current therapies are frequently unsatisfactory. We …

OBJECTIVE. The purpose of this article is to discuss facilitators of and barriers to future
implementation of contrast-enhanced mammography (CEM) in the United States. CONCLUSION. …

Background The genetic and clinical heterogeneity of breast cancer makes the identification
of effective therapies challenging. We designed I-SPY 2, a phase 2, multicenter, adaptively …

Background Previous studies have independently validated the prognostic relevance of
residual cancer burden (RCB) after neoadjuvant chemotherapy. We used results from several …

A study of the plasma pharmacokinetics, tumor localization, and safety of a single dose of
doxorubicin encapsulated in liposomes containing surface‐bound polyethylene glycol (PEG‐…

Background Reduced doses of cytotoxic chemotherapy or standard-dose therapy plus a
myeloid colony-stimulating factor decreases hematologic toxicity and its complications in …

Background The heterogeneity of breast cancer makes identifying effective therapies challenging.
The I-SPY 2 trial, a multicenter, adaptive phase 2 trial of neoadjuvant therapy for high-…

Background: Preclinical data indicate that docetaxel, platinum salts, and the combination of
both drugs are highly synergistic with the anti-HER2 antibody trastuzumab. The University of …