User profiles for D. W. Youngstrom
 | Daniel W. YoungstromUniversity of Connecticut Health Center, Department of Orthopaedic Surgery Verified email at uchc.edu Cited by 828 |
[HTML][HTML] Engineering tendon: scaffolds, bioreactors, and models of regeneration
DW Youngstrom, JG Barrett - Stem Cells International, 2016 - hindawi.com
Tendons bridge muscle and bone, translating forces to the skeleton and increasing the
safety and efficiency of locomotion. When tendons fail or degenerate, there are no effective …
safety and efficiency of locomotion. When tendons fail or degenerate, there are no effective …
Genetically engineered zebrafish as models of skeletal development and regeneration
Zebrafish (Danio rerio) are aquatic vertebrates with significant homology to their terrestrial
counterparts. While zebrafish have a centuries-long track record in developmental and …
counterparts. While zebrafish have a centuries-long track record in developmental and …
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight
…, R Rydzik, DW Youngstrom… - Proceedings of the …, 2020 - National Acad Sciences
Among the physiological consequences of extended spaceflight are loss of skeletal muscle
and bone mass. One signaling pathway that plays an important role in maintaining muscle …
and bone mass. One signaling pathway that plays an important role in maintaining muscle …
[HTML][HTML] Functional characterization of detergent-decellularized equine tendon extracellular matrix for tissue engineering applications
Natural extracellular matrix provides a number of distinct advantages for engineering replacement
orthopedic tissue due to its intrinsic functional properties. The goal of this study was to …
orthopedic tissue due to its intrinsic functional properties. The goal of this study was to …
A bioreactor system for in vitro tendon differentiation and tendon tissue engineering
There is significant clinical demand for functional tendon grafts in human and veterinary
medicine. Tissue engineering techniques combining cells, scaffolds, and environmental stimuli …
medicine. Tissue engineering techniques combining cells, scaffolds, and environmental stimuli …
Tenogenesis of bone marrow-, adipose-, and tendon-derived stem cells in a dynamic bioreactor
DW Youngstrom, JE LaDow… - Connective Tissue …, 2016 - Taylor & Francis
… YoungstromProgram in Biomedical and Veterinary Sciences, Marion duPont Scott Equine
Medical Center, … Youngstrom and Jade E. LaDow report no conflicts of interest. Jennifer G. …
Medical Center, … Youngstrom and Jade E. LaDow report no conflicts of interest. Jennifer G. …
Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A
…, R Rydzik, DW Youngstrom… - Proceedings of the …, 2020 - National Acad Sciences
Myostatin (MSTN) is a transforming growth factor-β (TGF-β) family member that normally acts
to limit muscle growth. The function of MSTN is partially redundant with that of another TGF-…
to limit muscle growth. The function of MSTN is partially redundant with that of another TGF-…
[HTML][HTML] Jagged1 expression by osteoblast-lineage cells regulates trabecular bone mass and periosteal expansion in mice
DW Youngstrom, MI Dishowitz, CB Bales, E Carr… - Bone, 2016 - Elsevier
Loss-of-function mutations in the Notch ligand, Jagged1 (Jag1), result in multi-system
developmental pathologies associated with Alagille syndrome (ALGS). ALGS patients present with …
developmental pathologies associated with Alagille syndrome (ALGS). ALGS patients present with …
Silver-doped bioactive glass particles for in vivo bone tissue regeneration and enhanced methicillin-resistant Staphylococcus aureus (MRSA) inhibition
Infection is a significant risk factor for failed healing of bone and other tissues. We have
developed a sol-gel (solution-gelation) derived bioactive glass doped with silver ions (Ag-BG), …
developed a sol-gel (solution-gelation) derived bioactive glass doped with silver ions (Ag-BG), …
[HTML][HTML] Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects
DW Youngstrom, R Senos, RL Zondervan… - NPJ Regenerative …, 2017 - nature.com
Each year, 33% of US citizens suffer from a musculoskeletal condition that requires medical
intervention, with direct medical costs approaching $1 trillion USD per year. Despite the …
intervention, with direct medical costs approaching $1 trillion USD per year. Despite the …