Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …

Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy (AAK). …

Loss of pluripotency is a gradual event whose initiating factors are largely unknown. Here we
report the earliest metabolic changes induced during the first hours of differentiation. High-…

The epidermis, the outer layer of the skin composed of keratinocytes, is a stratified epithelium
that functions as a barrier to protect the organism from dehydration and external insults. …

Pyloric atresia associated with junctional epidermolysis bullosa (PA–JEB), is a rare
inherited disorder characterized by pyloric stenosis and blistering of the skin as primary …

One of the prevailing hypotheses suggests schizophrenia as a neurodevelopmental disorder,
involving dysfunction of dopaminergic and glutamatergic systems. Accumulating evidence …

Cicatricial pemphigoid (CP) is an autoimmune blistering disease that primarily affects mucosal
tissues. Autoantibodies to laminin-5 have previously been detected in certain patients …

Mitogen-activated protein kinase (MAPK) pathways represent ubiquitous cellular signal
transduction pathways that regulate all aspects of life and are frequently altered in disease. Once …

… Basement membranes of sweat glands do not react with antibody SE144 (d, inset) but are …
Lanes are also designated by the pedigree L numbers (Fig.2), d, Schematic depiction of a wild …

The p53 family member TAp73 is a transcription factor that plays a key role in many biological
processes, including neuronal development. In particular, we have shown that p73 drives …