User profiles for D. Angeles-Albores

David Angeles-Albores

Sr. Scientist, Altos Labs
Verified email at altoslabs.com
Cited by 645

[HTML][HTML] Design and testing of a humanized porcine donor for xenotransplantation

…, T Tomosugi, Y Xue, GE Zentner, D Angeles-Albores… - Nature, 2023 - nature.com
Recent human decedent model studies 1 , 2 and compassionate xenograft use 3 have explored
the promise of porcine organs for human transplantation. To proceed to human studies, …

Cutaneous angiosarcoma. Analysis of 434 cases from the surveillance, epidemiology, and end results program, 1973-2007

…, L Kostun, A Hart, D Angeles-Albores… - Annals of diagnostic …, 2011 - Elsevier
Cutaneous angiosarcoma is an aggressive malignant mesenchymal vasoformative neoplasm
that accounts for 1% of all soft tissue sarcomas. Using data from the National Cancer …

[HTML][HTML] Tissue enrichment analysis for C. elegans genomics

D Angeles-Albores, RY N. Lee, J Chan… - BMC …, 2016 - Springer
Background Over the last ten years, there has been explosive development in methods for
measuring gene expression. These methods can identify thousands of genes altered …

[HTML][HTML] Two new functions in the WormBase Enrichment Suite

D Angeles-Albores, RYN Lee, J Chan… - microPublication …, 2018 - ncbi.nlm.nih.gov
… Using the methods described in Angeles-Albores et al, we generated ontology dictionaries
using the Anatomy, Phenotype and Gene Ontology annotations for C. elegans. The dictionary …

A male pheromone that improves the quality of the oogenic germline

…, S Dzitoyeva, D Angeles-Albores… - Proceedings of the …, 2022 - National Acad Sciences
Pheromones exchanged by conspecifics are a major class of chemical signals that can alter
behavior, physiology, and development. In particular, males and females communicate with …

Heat-shock proteases promote survival of Pseudomonas aeruginosa during growth arrest

DW Basta, D Angeles-Albores… - Proceedings of the …, 2020 - National Acad Sciences
When nutrients in their environment are exhausted, bacterial cells become arrested for growth.
During these periods, a primary challenge is maintaining cellular integrity with a reduced …

The Caenorhabditis elegans Female-Like State: Decoupling the Transcriptomic Effects of Aging and Sperm Status

D Angeles-Albores, DHW Leighton… - G3: Genes …, 2017 - academic.oup.com
… elegans during the first 6 d of adulthood, we measured the transcriptomes of first-day adult
hermaphrodites and sixth-day sperm-depleted adults, and, at the same time points, mutant fog…

Reconstructing a metazoan genetic pathway with transcriptome-wide epistasis measurements

D Angeles-Albores… - Proceedings of the …, 2018 - National Acad Sciences
RNA-sequencing (RNA-seq) is commonly used to identify genetic modules that respond to
perturbations. In single cells, transcriptomes have been used as phenotypes, but this concept …

A Caenorhabditis elegans Male Pheromone Feminizes Germline Gene Expression in Hermaphrodites and Imposes Life-History Costs

D Angeles-Albores, EZ Aprison… - Molecular biology …, 2023 - academic.oup.com
Sex pheromones not only improve the reproductive success of the recipients, but also
impose costs, such as a reduced life span. The underlying mechanisms largely remain to be …

Low-level resource partitioning supports coexistence among functionally redundant bacteria during successional dynamics

…, JH Hehemann, D Angeles-Albores… - The ISME …, 2024 - academic.oup.com
Members of microbial communities can substantially overlap in substrate use. However,
what enables functionally redundant microorganisms to coassemble or even stably coexist …