… The appearance of the photoreceptors in C and D is a post-mortem artifact unrelated to
the finding of drusen. INL: inner nuclear layer, OPL: outer plexiform layer, ONL: outer nuclear …

BACKGROUND A large portion of intronic and intergenic space in our genome consists of
repeated sequences. One of the most prevalent is the long interspersed element-1 (LINE-1, L1…

About half of all cancers have somatic integrations of retrotransposons. Here, to characterize
their role in oncogenesis, we analyzed the patterns and mechanisms of somatic …

… Thus, pyroptosis is not a neat, orderly shrinking and phagocytosis of cells in the way that
apoptosis is, but occurs quickly and leads to inflammation (Figure 1B,D). Our knowledge now of …

Interspersed repeat sequences comprise much of our DNA, although their functional effects
are poorly understood. The most commonly occurring repeat is the Alu short interspersed …

Transposable elements (TEs) are interspersed repeat sequences that make up much of the
human genome. Their expression has been implicated in development and disease. …

LINE-1 retrotransposon overexpression is a hallmark of human cancers. We identified a
colorectal cancer wherein a fast-growing tumor subclone downregulated LINE-1, prompting us …

… -uniform filament roads (marked by 1) and oozing (marked by 2), were also observed on
the surface of the black tensile samples printed at temperatures higher than 230 C (Figure 4d,e). …

… (D) Splicing assays were performed and are shown as in (B). At this locus, the polymorphic
… (D) Splicing assays were performed and are shown as in (B). At this locus, the polymorphic …

In the published version of this paper, the members of the Pan-Cancer Analysis of Whole
Genomes (PCAWG) Consortium were listed in the Supplementary Information; however, these …