The development of two-component expression systems in Drosophila melanogaster, one of
the most powerful genetic models, has allowed the precise manipulation of gene function in …

We use Caenorhabditis elegans to test proposed general rules for microRNA (miRNA)-target
interactions. We show that G·U base pairing is tolerated in the 'seed' region of the lsy-6 …

… c and d, Proliferation of CD8 + T cells stimulated with peptide-loaded aAPCs. d, Intracellular
… 3c and d ). When stimulated with A293 cells transfected with pp65 (A293-N pp65 + targets), …

… Target genes predicted by other prediction programs also did not show regulation in our
assay system (Didiano and Hobert 2006). Other features with proposed predictive values such …

OBJECTIVE: Damaged articular cartilage does not heal well and can progress to osteoarthritis
(OA). Human bone marrow stem cells (BMC) are promising cells for articular cartilage …

Heparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are
critical components of multiple signaling systems controlling neuronal development [1–3]. The …

… (D) Proliferating cells were counted across whole sections by PCNA staining for pretreatment
(n = 16 eyes analyzed), PBS injection (n = 40), and gabazine injection (n = 31). hpi, hours …

We describe here the results of genetic screens for Caenorhabditis elegans mutants in which
a single neuronal fate decision is inappropriately executed. In wild-type animals, the two …

Unlike the adult mammalian retina, Müller glia (MG) in the adult zebrafish retina are able to
dedifferentiate into a "stem cell"-like state and give rise to multipotent progenitor cells upon …

Primitive neuroectodermal tumors (PNETs), including medulloblastoma (PNET/MB) and
supratentorial PNET (sPNET), are the most common malignant brain tumors of childhood. The …