User profiles for D. Glass

David J. Glass

Regeneron Pharmaceuticals
Verified email at regeneron.com
Cited by 42885

[PDF][PDF] Cancer cachexia: mediators, signaling, and metabolic pathways

KCH Fearon, DJ Glass, DC Guttridge - Cell metabolism, 2012 - cell.com
Cancer cachexia is characterized by a significant reduction in body weight resulting
predominantly from loss of adipose tissue and skeletal muscle. Cachexia causes reduced cancer …

[BOOK][B] Behavior patterns, stress, and coronary disease.

DC Glass - 1977 - psycnet.apa.org
Reviews empirical literature documenting the relationship between coronary disease, stress,
and the Type A coronary prone behavior pattern. New data are presented concerning the …

Skeletal muscle hypertrophy and atrophy signaling pathways

DJ Glass - The international journal of biochemistry & cell biology, 2005 - Elsevier
Skeletal muscle hypertrophy is defined as an increase in muscle mass, which in the adult
animal comes as a result of an increase in the size, as opposed to the number, of pre-existing …

Identification of ubiquitin ligases required for skeletal muscle atrophy

…, TM DeChiara, TN Stitt, GD Yancopoulos, DJ Glass - Science, 2001 - science.org
Skeletal muscle adapts to decreases in activity and load by undergoing atrophy. To identify
candidate molecular mediators of muscle atrophy, we performed transcript profiling. Although …

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

…, A Scrimgeour, JC Lawrence, DJ Glass… - Nature cell …, 2001 - nature.com
… Muscles were taken after control (Con.), 14 d of HLS, 14 d of HLS followed by 7 d of recovery
(Rec.), and 14 d of HLS followed by 7 d of recovery plus treatment with cyclosporin (Rec. + …

National Institute of Mental Health treatment of depression collaborative research program: General effectiveness of treatments

…, SM Sotsky, JF Collins, DR Glass… - Archives of general …, 1989 - jamanetwork.com
• We investigated the effectiveness of two brief psychotherapies, interpersonal psychotherapy
and cognitive behavior therapy, for the treatment of outpatients with major depressive …

[HTML][HTML] The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

…, WO Kline, M Gonzalez, GD Yancopoulos, DJ Glass - Molecular cell, 2004 - cell.com
Skeletal muscle size depends upon a dynamic balance between anabolic (or hypertrophic)
and catabolic (or atrophic) processes. Previously, no link between the molecular mediators …

International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001

…, P Manners, J Baum, DN Glass… - The Journal of …, 2004 - pubmed.ncbi.nlm.nih.gov
… 1 , Taunton R Southwood, Prudence Manners, John Baum, David N Glass, Jose
Goldenberg, Xiaohu He, Jose Maldonado-Cocco, Javier Orozco-Alcala, Anne-Marie Prieur …

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI (3) K/Akt/mTOR and PI (3) K/Akt/GSK3 pathways

…, L Nunez, TN Stitt, GD Yancopoulos, DJ Glass - Nature cell …, 2001 - nature.com
Skeletal muscle is composed of multinucleated fibres, formed after the differentiation and
fusion of myoblast precursors 1 . Skeletal muscle atrophy and hypertrophy refer to changes in …

[PDF][PDF] Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

DA Glass, P Bialek, JD Ahn, M Starbuck, MS Patel… - Developmental cell, 2005 - cell.com
… (D) Left: Lower incisors are absent in a 3-week-old bcat(ex3)ob mouse. Right: X-ray analysis
of 3-week-old wt (top) and bcat(ex3)ob (bottom) skulls shows that lower incisors formed (…