Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion
…, N Sakai, I Yanagihara, M Yamada, D Van Gosliga… - Nature …, 2005 - nature.com
… We thank the families with Roberts syndrome for their interest and cooperation; D. Tomkins
for R22 sample; Biobank at the Istituto Giannina Gaslini for R34 sample; and M. Camargo for …
for R22 sample; Biobank at the Istituto Giannina Gaslini for R34 sample; and M. Camargo for …
Human salivary gland stem cells functionally restore radiation damaged salivary glands
…, M van der Zwaag, MA Stokman, D van Gosliga… - Stem …, 2016 - academic.oup.com
… Salisphere cultures of 3–5 day (d) were dispersed to form single cell suspensions using
0.05% trypsin-EDTA (Invitrogen), enumerated, and concentration adjusted to 0.4 × 10 6 cells per …
0.05% trypsin-EDTA (Invitrogen), enumerated, and concentration adjusted to 0.4 × 10 6 cells per …
[HTML][HTML] Resveratrol and pterostilbene inhibit SARS-CoV-2 replication in air–liquid interface cultured human primary bronchial epithelial cells
…, L Apperloo, D van Gosliga, M van den Berge… - Viruses, 2021 - mdpi.com
The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search …
2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search …
[HTML][HTML] Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells
D van Gosliga, H Schepers, A Rizo… - Experimental …, 2007 - Elsevier
OBJECTIVE: With the emergence of the concept of the leukemia stem cell, assays to study
them remain pivotal in understanding (leukemic) stem cell biology. METHODS: We have …
them remain pivotal in understanding (leukemic) stem cell biology. METHODS: We have …
STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells
H Schepers, D van Gosliga… - Blood, The Journal …, 2007 - ashpublications.org
The transcription factor STAT5 fulfills a distinct role in the hematopoietic system, but its
precise role in primitive human hematopoietic cells remains to be elucidated. Therefore, we …
precise role in primitive human hematopoietic cells remains to be elucidated. Therefore, we …
[HTML][HTML] A proteomics and transcriptomics approach to identify leukemic stem cell (LSC) markers
F Bonardi, F Fusetti, P Deelen, D van Gosliga… - Molecular & Cellular …, 2013 - ASBMB
Interactions between hematopoietic stem cells and their niche are mediated by proteins within
the plasma membrane (PM) and changes in these interactions might alter hematopoietic …
the plasma membrane (PM) and changes in these interactions might alter hematopoietic …
[HTML][HTML] The cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2
…, BC Godthelp, W van Zon, D van Gosliga… - PloS one, 2009 - journals.plos.org
Cohesion between sister chromatids is essential for faithful chromosome segregation. In
budding yeast, the acetyltransferase Eco1/Ctf7 establishes cohesion during DNA replication in …
budding yeast, the acetyltransferase Eco1/Ctf7 establishes cohesion during DNA replication in …
Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells
…, F Bonardi, D Malanga, D van Gosliga… - Blood, The Journal …, 2013 - ashpublications.org
… (D) CFC analysis of freshly transduced and replates of cells expressing SCRGFP/SCRCFP, …
(D) CFC analysis of freshly transduced and replates of cells expressing SCR GFP /SCR CFP …
(D) CFC analysis of freshly transduced and replates of cells expressing SCR GFP /SCR CFP …
Moxidectin and ivermectin inhibit SARS-CoV-2 replication in Vero E6 cells but not in human primary bronchial epithelial cells
…, D van Gosliga… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Antiviral therapies are urgently needed to treat and limit the development of severe COVID-19
disease. Ivermectin, a broad-spectrum anti-parasitic agent, has been shown to have anti-…
disease. Ivermectin, a broad-spectrum anti-parasitic agent, has been shown to have anti-…
Resveratrol and pterostilbene potently inhibit SARS-CoV-2 replication in vitro
…, L Apperloo, D van Gosliga, M van den Berge… - BioRxiv, 2020 - biorxiv.org
The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search …
2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search …