User profiles for D. Gysi

Deisy Morselli Gysi

Federal University of Paraná | Harvard Medical School | Northeastern University
Verified email at channing.harvard.edu
Cited by 875

[HTML][HTML] Improving the generalizability of protein-ligand binding predictions with AI-Bind

…, Z Shafi, OS Ahmed, M Sebek, D Gysi… - Nature …, 2023 - nature.com
… Furthermore, we observe lower variability in K d values across links originating from high-degree
nodes, compared to lower-degree nodes (see Supplementary Note 1). As the …

A wealth of discovery built on the Human Genome Project—by the numbers

AJ Gates, DM Gysi, M Kellis, AL Barabási - Nature, 2021 - nature.com
… Deisy Morselli Gysi … Deisy Morselli Gysi … Deisy Morselli Gysi is a postdoctoral research
associate at the Network Science Institute, Northeastern University, Boston, Massachusetts, USA …

Construction, comparison and evolution of networks in life sciences and other disciplines

DM Gysi, K Nowick - Journal of the Royal Society …, 2020 - royalsocietypublishing.org
Network approaches have become pervasive in many research fields. They allow for a more
comprehensive understanding of complex relationships between entities as well as their …

[HTML][HTML] wTO: an R package for computing weighted topological overlap and a consensus network with integrated visualization tool

DM Gysi, A Voigt, TM Fragoso, E Almaas, K Nowick - BMC bioinformatics, 2018 - Springer
Background Network analyses, such as of gene co-expression networks, metabolic networks
and ecological networks have become a central approach for the systems-level study of …

[PDF][PDF] Combined experimental and system-level analyses reveal the complex regulatory network of miR-124 during human neurogenesis

LK Kutsche, DM Gysi, J Fallmann, K Lenk, R Petri… - Cell systems, 2018 - cell.com
Non-coding RNAs regulate many biological processes including neurogenesis. The brain-enriched
miR-124 has been assigned as a key player of neuronal differentiation via its …

[HTML][HTML] Seasonal dynamics of pelagic mycoplanktonic communities: interplay of taxon abundance, temporal occurrence, and biotic interactions

S Banos, DM Gysi, T Richter-Heitmann… - Frontiers in …, 2020 - frontiersin.org
Marine fungi are an important component of pelagic planktonic communities. However, it is
not yet clear how individual fungal taxa are integrated in marine processes of the microbial …

Current and future directions in network biology

M Zitnik, MM Li, A Wells, K Glass, DM Gysi… - arXiv preprint arXiv …, 2023 - arxiv.org
… For some TFs, altered DNA-binding specificities can be predicted de novo using machine
learning [62, 325, 354, 443]. However, if a DNA-binding protein’s specificity is known a priori, …

Measuring hand hygiene compliance rates at hospital entrances

…, TZS Camargo, E da Silva Victor, DM Gysi… - American journal of …, 2015 - Elsevier
… At entrance D, we had 8,277 opportunities for hand hygiene detected by the human
observer and 140 hand hygiene episodes, with an overall compliance rate of 1.7%. …

[HTML][HTML] Centrality measures in psychological networks: A simulation study on identifying effective treatment targets

D Castro, D Gysi, F Ferreira, F Ferreira-Santos… - Plos one, 2024 - journals.plos.org
The network theory of psychopathology suggests that symptoms in a disorder form a network
and that identifying central symptoms within this network might be important for an effective …

Ai-bind: improving binding predictions for novel protein targets and ligands

…, Z Shafi, OS Ahmed, M Sebek, D Gysi… - arXiv preprint arXiv …, 2021 - arxiv.org
Identifying novel drug-target interactions (DTI) is a critical and rate limiting step in drug
discovery. While deep learning models have been proposed to accelerate the identification …