Background Concerns regarding the safety of transfused blood have led to the development
of a range of interventions to minimise blood loss during major surgery. Anti‐fibrinolytic …

Background A number of approaches have been used to grade levels of evidence and the
strength of recommendations. The use of many different approaches detracts from one of the …

… , summary relative risk with 25 mg/d or less, 1.33 (95% confidence interval [CI], 1.00-1.79)
and 2.19 (95% CI, 1.64-2.91) with more than 25 mg/d. The risk was elevated during the first …

… ε (6) If A is sectorial in X and B is a linear operator D(B) = D(A) and for all x ED(A) | Bx || < ||
Ax || + K(E) ||x|| (for sufficiently small ε > 0) then A+B is sectorial (see Th. 1.3.2). (7) An …

Non-randomised studies of the effects of interventions are critical to many areas of healthcare
evaluation, but their results may be biased. It is therefore important to understand and …

… www.sign.ac.uk/checklists-and-notes.html 61 McGettigan P, Henry D. Cardiovascular risk
with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled …

… double layer, Smoluchowski deduced the expression U = DXζ/4πη (1) for the cataphoretic
velocity U ; X is the applied field strength, ζ the potential difference across the double layer, D …

… A publicly funded and independently run programme of “de-medicalisation,” based on
respect for human dignity, rather than shareholder value or professional hubris, is overdue. …

OBJECTIVE: Our purpose was to measure the agreement, reliability, construct validity, and
feasibility of a measurement tool to assess systematic reviews (AMSTAR). STUDY DESIGN …

Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …