… Rowe, J Alexandra a ; Opi, D Herbert a,b ; Williams, Thomas N b,c,d … Molecular
identification of Knops blood group polymorphisms found in long homologous region D of …

Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …

Developing efficacious vaccines for human malaria caused by Plasmodium falciparum is a
major global health priority, although this has proven to be immensely challenging over the …

Antibodies against P. falciparum merozoites fix complement to inhibit blood-stage replication
in naturally-acquired and vaccine-induced immunity; however, specific targets of these …

Background Low birth weight (LBW) and preterm birth (PTB) are major contributors to infant
mortality and chronic childhood morbidity. Understanding factors that contribute to or protect …

Malaria vaccines are urgently needed in the fight against this devastating disease that is
responsible for almost half a million deaths each year. Here, we discuss recent clinical …

10.7554/eLife.31579.001 Malaria has been a major driving force in the evolution of the
human genome. In sub-Saharan African populations, two neighbouring polymorphisms in the …

Background Individually, the red blood cell (RBC) polymorphisms sickle cell trait (HbAS) and
α + thalassemia protect against severe Plasmodium falciparum malaria. It has been shown …

Introduction A vaccine would greatly accelerate current global efforts toward malaria elimination.
While a partially efficacious vaccine has been achieved for Plasmodium falciparum, a …

Background The pathogenesis of malaria in pregnancy (MiP) involves accumulation of P.
falciparum-infected red blood cells (pRBCs) in the placenta, contributing to poor pregnancy …