Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

Z Liao, D Lockhead, ED Larson… - Journal of General …, 2010 - rupress.org
The sympathetic nervous system increases heart rate by activating β adrenergic receptors
and increasing cAMP levels in myocytes in the sinoatrial node. The molecular basis for this …

[PDF][PDF] Phospholipids that contain polyunsaturated fatty acids enhance neuronal cell mechanics and touch sensation

V Vásquez, M Krieg, D Lockhead, MB Goodman - Cell reports, 2014 - cell.com
… (D) Touch response after knocking down mboa-6 in transgenic worms that express sid-1
exclusively in neurons and after supplementing NGM with the AA-containing phospholipids. PC, …

The tubulin repertoire of Caenorhabditis elegans sensory neurons and its context‑dependent role in process outgrowth

D Lockhead, EM Schwarz, R O'Hagan… - Molecular biology of …, 2016 - Am Soc Cell Biol
… for 3 d; hygromycin was then added to the plates to a final concentration of 250 μg/ml to select
for transgenic animals and putative knock‑in lines. After 3–5 d of … After 3 d, we screened for …

[BOOK][B] The dialogical imperative: A Christian reflection on interfaith encounter

D Lochhead - 2012 - books.google.com
… David Lochhead first differentiates between several … Lochhead brings fresh insights to a
reading of Barth on the … Based on this, Lochhead proposes a stance of" faithful agnosticism"--the …

Cellular context and multiple channel domains determine cAMP sensitivity of HCN4 channels: Ligand-independent relief of autoinhibition in HCN4

Z Liao, D Lockhead, JR St. Clair, ED Larson… - Journal of General …, 2012 - rupress.org
Hyperpolarization-activated, cyclic nucleotide–sensitive (HCN) channels produce the I f and
I h currents, which are critical for cardiac pacemaking and neuronal excitability, respectively. …

Synthesis and Structure−Activity Relationship of Novel 6-Aryl-1,4- dihydrobenzo[d][1,3]oxazine-2-thiones as Progesterone Receptor Modulators Leading to the Potent …

…, V Hudak, K Malakian, S Lockhead… - Journal of medicinal …, 2005 - ACS Publications
Tanaproget represents a potential first-in-class nonsteroidal PR agonist for contraception
with improved safety and side effect profiles versus currently available steroidal oral …

Atlantic Regionalism and Literature: Some Bibliographical Comments.

D Lochhead - Essays on Canadian Writing, 1985 - search.ebscohost.com
… (d) Scholarly journals continue to include an increasing number of critical articles on
Atlantic literature. The most substantial scholarly study to appear in recent years is Patrick O'…

[HTML][HTML] Long-term colorectal-cancer incidence and mortality after lower endoscopy

R Nishihara, K Wu, P Lochhead… - … England Journal of …, 2013 - Mass Medical Soc
Background Colonoscopy and sigmoidoscopy provide protection against colorectal cancer,
but the magnitude and duration of protection, particularly against cancer of the proximal …

[HTML][HTML] Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival

X Liao, P Lochhead, R Nishihara… - … England Journal of …, 2012 - Mass Medical Soc
Background Regular use of aspirin after a diagnosis of colon cancer has been associated
with a superior clinical outcome. Experimental evidence suggests that inhibition of …

[BOOK][B] Problem solving & comprehension

A Whimbey, J Lochhead, R Narode - 2013 - taylorfrancis.com
… They’d be happy to gain increased capability to reason—because in today’s world it’s
almost impossible to avoid doing some problem solving and technical reading. The business …