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Deepak MalhotraProfessor of Negotiations, Harvard Business School Verified email at hbs.edu Cited by 7266 |
[HTML][HTML] CNVs: harbingers of a rare variant revolution in psychiatric genetics
D Malhotra, J Sebat - Cell, 2012 - cell.com
The genetic bases of neuropsychiatric disorders are beginning to yield to scientific inquiry.
Genome-wide studies of copy number variation (CNV) have given rise to a new …
Genome-wide studies of copy number variation (CNV) have given rise to a new …
Hematology: issues in the dialysis patient: platelet dysfunction and end‐stage renal disease
D Kaw, D Malhotra - Seminars in dialysis, 2006 - Wiley Online Library
Patients with end‐stage renal disease (ESRD) develop hemostatic disorders mainly in the
form of bleeding diatheses. Hemorrhage can occur at cutaneous, mucosal, or serosal sites. …
form of bleeding diatheses. Hemorrhage can occur at cutaneous, mucosal, or serosal sites. …
Normal acts of irrational trust: Motivated attributions and the trust development process
This paper presents a new, motivated attributions model of trust development. The model
builds on two simple insights: that the parties in a potentially trusting relationship are likely to …
builds on two simple insights: that the parties in a potentially trusting relationship are likely to …
Strong association of de novo copy number mutations with autism
We tested the hypothesis that de novo copy number variation (CNV) is associated with autism
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …
Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain
elusive. We hypothesize that individually rare structural variants contribute to the illness. …
elusive. We hypothesize that individually rare structural variants contribute to the illness. …
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
…, D Pinto, M Gujral, WM Brandler, D Malhotra… - Nature …, 2017 - nature.com
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …
Microduplications of 16p11. 2 are associated with schizophrenia
Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
D Malhotra, E Portales-Casamar, A Singh… - Nucleic acids …, 2010 - academic.oup.com
The Nrf2 (nuclear factor E2 p45-related factor 2) transcription factor responds to diverse
oxidative and electrophilic environmental stresses by circumventing repression by Keap1, …
oxidative and electrophilic environmental stresses by circumventing repression by Keap1, …
The effects of contracts on interpersonal trust
D Malhotra, JK Murnighan - Administrative science quarterly, 2002 - journals.sagepub.com
This paper uses two laboratory experiments to investigate the effects of contracts on interpersonal
trust. We predict that the use of binding contracts to promote or mandate cooperation …
trust. We predict that the use of binding contracts to promote or mandate cooperation …
[HTML][HTML] Whole-genome sequencing in autism identifies hot spots for de novo germline mutation
De novo mutation plays an important role in autism spectrum disorders (ASDs). Notably,
pathogenic copy number variants (CNVs) are characterized by high mutation rates. We …
pathogenic copy number variants (CNVs) are characterized by high mutation rates. We …