The idea that liquid–liquid phase separation (LLPS) may be a general mechanism by which
molecules in the complex cellular milieu may self-organize has generated much excitement …

… ,e, LLPS of MBP-hCTD in 16% dextran shows little sensitivity to ionic strength changes (d)
and is stable during incubation of the sample at different temperatures for 1 h (e). Images …

TERT promoter mutations (TPMs) are the most common noncoding mutations in cancer.
The timing and consequences of TPMs have not been fully established. Here, we show that …

… (D) Jump length distributions between consecutive frames of spaSPT trajectories. … (D)
Quantification of the ICP0 intron signal in untreated cells (n = 170 RCs) those treated with TRP(n = …

10.7554/eLife.27417.001 Differentiation programs such as meiosis depend on extensive
gene regulation to mediate cellular morphogenesis. Meiosis requires transient removal of the …

Cas9 is a prokaryotic RNA-guided DNA endonuclease that binds substrates tightly in vitro
but turns over rapidly when used to manipulate genomes in eukaryotic cells. Little is known …

Single molecule fluorescence in situ hybridization (smFISH) is a powerful technique to study
gene expression in single cells due to its ability to detect and count individual RNA …

10.7554/eLife.48193.001 A central problem in human biology remains the discovery of
causal molecular links between mutations identified in genome-wide association studies (GWAS) …

… Une nette augmentation du taux d'isolement de Mycobacterium xenopi à partir de produits
cliniques a incité à entreprendre une étude du système de distribution d'eau, à la recherche d'…

… D free we defined as the occupation-weighted average diffusion coefficient of the non-bound
states (Extended data 2C). Some SHRs had a higher proportion of bound molecules than …