… (D) Mathematical model simulation predicts that Ire1 bipless would display delayed … 3C,D)
is sterically hindered by the long helix αB in the human structure, which forms a new, smaller …

The focus of this review is the evolution of biochemical phenotypic yeast identification methods
with emphasis on conventional approaches, rapid screening tests, chromogenic agars, …

… Although highly detailed description and results of the study can be found elsewhere (Pincus,
1999), the study will be summarized below to highlight the details of the intervention …

The application of all‐atom force fields (and explicit or implicit solvent models) to protein
homology‐modeling tasks such as side‐chain and loop prediction remains challenging both …

Choanoflagellates are the closest known relatives of metazoans. To discover potential
molecular mechanisms underlying the evolution of metazoan multicellularity, we sequenced and …

The beclin 1 (BECN1) gene encodes a 60-kDa coiled-coil protein that interacts with the
prototypic apoptosis inhibitor Bcl-2. Previous studies indicate that beclin 1 maps to a region …

… -, 30- and 36-hour thresholds (eAppendix D in the Supplement). Delayed hip fracture surgery
was … Author Contributions: Dr Pincus had full access to all of the data in the study and takes …

Right-hemisphere brain damaged (RHD) patients and a normal control group were tested
for their ability to infer first- and second-order mental states and to understand the …

The unfolded protein response (UPR) is an intracellular signaling pathway that counteracts
variable stresses that impair protein folding in the endoplasmic reticulum (ER). As such, the …

Deficiencies in the protein-folding capacity of the endoplasmic reticulum (ER) in all eukaryotic
cells lead to ER stress and trigger the unfolded protein response (UPR) 1 , 2 , 3 . ER stress …