User profiles for D. RAMAZZOTTI
Daniele RamazzottiDepartment of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy Verified email at unimib.it Cited by 2651 |
Visualization and analysis of single-cell RNA-seq data by kernel-based similarity learning
We present single-cell interpretation via multikernel learning (SIMLR), an analytic framework
and software which learns a similarity measure from single-cell RNA-seq data in order to …
and software which learns a similarity measure from single-cell RNA-seq data in order to …
[HTML][HTML] Data pre-processing
B Malley, D Ramazzotti, JTY Wu - 2019 - europepmc.org
Data pre-processing consists of a series of steps to transform raw data derived from data
extraction (see Chap. 11) into a “clean” and “tidy” dataset prior to statistical analysis. Research …
extraction (see Chap. 11) into a “clean” and “tidy” dataset prior to statistical analysis. Research …
[HTML][HTML] Phenotypic plasticity and genetic control in colorectal cancer evolution
Genetic and epigenetic variation, together with transcriptional plasticity, contribute to
intratumour heterogeneity 1 . The interplay of these biological processes and their respective …
intratumour heterogeneity 1 . The interplay of these biological processes and their respective …
[HTML][HTML] The co-evolution of the genome and epigenome in colorectal cancer
Colorectal malignancies are a leading cause of cancer-related death 1 and have undergone
extensive genomic study 2 , 3 . However, DNA mutations alone do not fully explain …
extensive genomic study 2 , 3 . However, DNA mutations alone do not fully explain …
Detecting repeated cancer evolution from multi-region tumor sequencing data
G Caravagna, Y Giarratano, D Ramazzotti… - Nature …, 2018 - nature.com
… With input CCF, each entry of D i is a real value in [0,1]; with binary data 1 is used to report
where the alteration is detected. We assume that D i has no 0 columns and denote as {D i |i = …
where the alteration is detected. We assume that D i has no 0 columns and denote as {D i |i = …
[HTML][HTML] Multi-omic tumor data reveal diversity of molecular mechanisms that correlate with survival
… The clusters are evaluated by visualization as a 2-D scatter plot and survival analysis. The
molecular features significantly enriched in each cluster are listed, and finally, pathway activity …
molecular features significantly enriched in each cluster are listed, and finally, pathway activity …
Use of collagen scaffold and autologous bone marrow concentrate as a one-step cartilage repair in the knee: histological results of second-look biopsies at 1 year …
…, D Ramazzotti, S Manzotti, D Enea - International journal …, 2011 - journals.sagepub.com
Chondral articular defects are a key concern in orthopaedic surgery. To overcome the
disadvantages of autologous chondrocyte implantation (ACI) and to improve the outcomes of …
disadvantages of autologous chondrocyte implantation (ACI) and to improve the outcomes of …
[PDF][PDF] Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity
… (D) Bar plot returning the proportion of sites of the SARS-CoV-2 genome that are either
non-… In this work, we followed the guidelines proposed in Ramazzotti et al. (2020) and applied …
non-… In this work, we followed the guidelines proposed in Ramazzotti et al. (2020) and applied …
CAPRI: efficient inference of cancer progression models from cross-sectional data
… in an m × n binary matrix D, in which an entry D i , j = 1 if the event j was observed in sample
i, and 0 otherwise. Assumption (iv) is satisfied when all columns in D differ—ie the alteration …
i, and 0 otherwise. Assumption (iv) is satisfied when all columns in D differ—ie the alteration …
[HTML][HTML] Exposing the probabilistic causal structure of discrimination
… We start with an input relational table D defined over a set A of h categorical attributes and s
… in D, we assume they have been discretized to become categorical. From D, we derive \(D^{\…
… in D, we assume they have been discretized to become categorical. From D, we derive \(D^{\…