The role of epigenetics in the modulation of longevity has not been studied in humans. To
this aim, (1) we evaluated the DNA methylation from peripheral leukocytes of 21 female …

PURPOSE Recurrently mutated genes and chromosomal abnormalities have been identified
in myelodysplastic syndromes (MDS). We aim to integrate these genomic features into …

In this paper we compared taxonomic results obtained by metataxonomics (16S rRNA gene
sequencing) and metagenomics (whole shotgun metagenomic sequencing) to investigate …

… where Φ is the fully specified factor graph, S ⊂ A i ( a ) ∪ D X j are all the possible configurations
consistent with both the dataset measurements D and the fact that gene i is activated (…

One of the most important challenges in network science is to quantify the information encoded
in complex network structures. Disentangling randomness from organizational principles …

Down Syndrome (DS) is characterized by a wide spectrum of clinical signs, which include
segmental premature aging of central nervous and immune systems. Although it is well …

Purpose The improvement of Ewing sarcoma (EWS) therapy is currently linked to the discovery
of strategies to select patients with poor and good prognosis and of modified treatment …

Recovery after cardiac surgery is a complex process that has to compensate for both individual
variability and extensive tissue damage in the context of systemic inflammation. Protein …

Background: The clinical application of freshly isolated connective-tissue progenitors, as
well as the potential preparation of culture-expanded mesenchymal stem cell populations for …

Background Detecting somatic mutations in whole exome sequencing data of cancer
samples has become a popular approach for profiling cancer development, progression and …