Mammalian circadian rhythms are controlled by endogenous biological oscillators, including
a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period …

GOLOMBEK, DA, P. PÉVET AND DP CARDINALI. Melatonin effects on behavior: possible
mediation by the central GABAergic system. NEUROSCI BIOBEHAV REV 20(3) 403–412, …

Circadian rhythms are endogenous and need to be continuously entrained (synchronized)
with the environment. Entrainment includes both coupling internal oscillators to external …

The COVID-19 pandemic [1] resulted in many countries imposing a lockdown, which in turn
reduces sunlight exposure and alters daily social schedules. Since these are the main …

Access to electric light might have shifted the ancestral timing and duration of human sleep.
To test this hypothesis, we studied two communities of the historically hunter-gatherer …

Circadian disruption negatively affects physiology, posing a global health threat that manifests
in proliferative, metabolic, and immune diseases, among others. Because outputs of the …

The orexigenic peptide ghrelin stimulates both food intake and growth hormone release and
is synthesized in the stomach and in hypothalamic areas involved in feeding control. The …

The aim of this study was to determine whether melatonin-induced analgesia in mice
exhibits the time dependency known to occur for several other effects of the hormone, and to …

Automation of simple behavioral patterns, such as locomotor activity, is fundamental for
pharmacological and genetic screening studies. Recently, circadian behaviors in locomotor …

Anxiolytic and pro-exploratory melatonin properties were assessed in rats using a plus-maze
procedure. Both melatonin (1 mg/kg) and diazepam (0.5 mg/kg) showed a significant …