… The authors thank members of the Gould and Pegtel laboratories for constructive comments
on early drafts of this review. This work was supported by a grant from the National Institutes …

Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological
conditions, the interest in EVs is exponentially growing. EVs hold high hopes for novel …

… , high levels of EV-associated 3′-uridilated miRNA isoforms seem to be present in
plasma vesicles obtained from cancer patients compared to their normal counterparts (Pegtel, …

Noncoding regulatory microRNAs (miRNAs) of cellular and viral origin control gene expression
by repressing the translation of mRNAs into protein. Interestingly, miRNAs are secreted …

Most cancer cells release heterogeneous populations of extracellular vesicles (EVs) containing
proteins, lipids, and nucleic acids. In vitro experiments showed that EV uptake can lead …

Introduction Administration of mesenchymal stem cells (MSCs) represents a promising
treatment option for patients suffering from immunological and degenerative disorders. …

The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids…

Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and
transmitted between mammalian cells via extracellular vesicles (EVs), including endosome-…

Mesenchymal stem cells (MSCs) are adult multipotent cells that give rise to various cell
types of the mesodermal germ layer. MSCs are of great interest in the field of regenerative …

Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …