User profiles for DE Orange
Didier OrangeIRD Verified email at ird.fr Cited by 3904 |
[HTML][HTML] Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
…, LB Ivashkiv, VP Bykerk, DE Orange… - Nature …, 2018 - nature.com
… d Microscope image screen capture directly from the instrument. Cells and barcoded
microparticles are visualized easily on the screen. e Microscope image of droplets output from the …
microparticles are visualized easily on the screen. e Microscope image of droplets output from the …
[HTML][HTML] Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
…, J Mears, K Slowikowski, K Weinand, DE Orange… - Nature, 2023 - nature.com
Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation
and destruction 1 . There is currently no cure for rheumatoid arthritis, and the effectiveness of …
and destruction 1 . There is currently no cure for rheumatoid arthritis, and the effectiveness of …
Identification of three rheumatoid arthritis disease subtypes by machine learning integration of synovial histologic features and RNA sequencing data
DE Orange, P Agius, EF DiCarlo… - Arthritis & …, 2018 - Wiley Online Library
Objective In this study, we sought to refine histologic scoring of rheumatoid arthritis ( RA )
synovial tissue by training with gene expression data and machine learning. Methods Twenty …
synovial tissue by training with gene expression data and machine learning. Methods Twenty …
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis
…, RB Darnell, WH Robinson, DE Orange - Science translational …, 2023 - science.org
Periodontal disease is more common in individuals with rheumatoid arthritis (RA) who have
detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal …
detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal …
[HTML][HTML] RNA identification of PRIME cells predicting rheumatoid arthritis flares
DE Orange, V Yao, K Sawicka, J Fak… - … England Journal of …, 2020 - Mass Medical Soc
Background Rheumatoid arthritis, like many inflammatory diseases, is characterized by
episodes of quiescence and exacerbation (flares). The molecular events leading to flares are …
episodes of quiescence and exacerbation (flares). The molecular events leading to flares are …
[BOOK][B] Emotional understanding: Studies in psychoanalytic epistemology
DM Orange - 1995 - books.google.com
… Orange illuminates the nature and process of psychoanalytic understanding within the
intimate and healing human context of treatment. Moving away from objectivist empiricism and its …
intimate and healing human context of treatment. Moving away from objectivist empiricism and its …
Runoff and sediment losses from 27 upland catchments in Southeast Asia: Impact of rapid land use changes and conservation practices
Rapid changes in upland farming systems in Southeast Asia generated predominantly by
increased population pressure and ‘market forces’ have resulted in widespread land …
increased population pressure and ‘market forces’ have resulted in widespread land …
Mitochondrial introgression and incomplete lineage sorting through space and time: phylogenetics of crotaphytid lizards
…, MS Koo, DW Hutchison, AK Lappin, DI Orange… - …, 2007 - academic.oup.com
We investigate the roles of mitochondrial introgression and incomplete lineage sorting
during the phylogenetic history of crotaphytid lizards. Our Bayesian phylogenetic estimate for …
during the phylogenetic history of crotaphytid lizards. Our Bayesian phylogenetic estimate for …
Cold-seeps and authigenic carbonate formation in Monterey Bay, California
DS Stakes, D Orange, JB Paduan, KA Salamy… - Marine Geology, 1999 - Elsevier
… as determined by microprobe; D=dolomite; F=feldspar; HMC=high Mg calcite; Q=quartz. …
(d) Note size range of spheroidal pyrite is 5–20 μm and each framboid is composed of …
(d) Note size range of spheroidal pyrite is 5–20 μm and each framboid is composed of …
[PDF][PDF] Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression
…, S Raychauduri, M Bombardieri, C Pitzalis, DE Orange… - Cell reports, 2022 - cell.com
Ectopic lymphoid structures (ELS) can develop in rheumatoid arthritis (RA) synovial tissue,
but the precise pathways of B cell activation and selection are not well understood. Here, we …
but the precise pathways of B cell activation and selection are not well understood. Here, we …