User profiles for DI Boomsma

Dorret Boomsma

Netherlands Twin Register, VU Amsterdam
Verified email at vu.nl
Cited by 191159

[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

…, HJ Bockholt, E Bøen, C Bois, DI Boomsma… - Brain imaging and …, 2014 - Springer
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …

Evolutionary mechanisms for loneliness

JT Cacioppo, S Cacioppo, DI Boomsma - Cognition & emotion, 2014 - Taylor & Francis
… A gender difference in prevalence was found, but the results of Boomsma et al. (Citation2005)
suggest that gender differences are environmentally (eg, social norms, cultural influences) …

Genetic influences on human brain structure: a review of brain imaging studies in twins

JS Peper, RM Brouwer, DI Boomsma… - Human brain …, 2007 - Wiley Online Library
Twin studies suggest that variation in human brain volume is genetically influenced. The
genes involved in human brain volume variation are still largely unknown, but several …

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

…, H Ahsan, BL Pierce, T Lehtimäki, DI Boomsma… - Nature …, 2021 - nature.com
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms
on the transcriptome. To investigate the genetics of gene expression, we performed cis…

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

…, P Asherson, CL Burton, DI Boomsma… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Integrative approaches for large-scale transcriptome-wide association studies

…, R Jansen, EJC De Geus, DI Boomsma… - Nature …, 2016 - nature.com
Many genetic variants influence complex traits by modulating gene expression, thus altering
the abundance of one or multiple proteins. Here we introduce a powerful strategy that …

Large-scale association analyses identify host factors influencing human gut microbiome composition

…, JT Bell, H Bisgaard, M Boehnke, DI Boomsma… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

…, JD Boardman, M Boehnke, DI Boomsma… - Nature …, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

…, M Bochud, M Boehnke, E Boerwinkle, DI Boomsma… - Nature …, 2018 - nature.com
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

Genetic influence on cytokine production and fatal meningococcal disease

…, TWJ Huizinga, AH Elouali, CL Verweij, DI Boomsma… - The Lancet, 1997 - thelancet.com
Background To assess the genetic influence on cytokine production and its contribution to
fatal outcome, we determined the capacity to produce tumour necrosis factor-α (TNFα) and …